“…This implies, at least for Markovian systems, the existence of steady-state probability currents in the state space, which change sign under time-reversal. When a thermodynamically consistent description is available, the average rate of entropy production can be related to the rate of energy or information exchange between the system, the heat bath(s) it is connected to, and any other thermodynamic entity involved in the dynamics, such as a measuring device [ 15 , 16 , 17 ]. Whilst the rate of energy dissipation is of immediate interest since it captures how ‘costly’ it is to sustain specific dynamics (e.g., the metabolism sustaining the development of an organism [ 18 , 19 ]), entropy production has also been found to relate non-trivially to the efficiency and precision of the corresponding process via uncertainty relations [ 3 , 20 ].…”