Heat Transfer and Hydrodynamics in Preparative Continuous Annular Chromatography (P-CAC)

Continuous annular chromatography (CAC) is a separation process for multicomponent liquid mixtures. The performance of the apparatus can be seriously decreased by temperature gradients inside the adsorbent bed. It is shown, that the temperature gradients can be significantly reduced by a pre-heating of the entering liquid in the apparatus itself. Heat transfer and hydrodynamics in the porous media are described by two different modelling approaches. Both are based on a pseudo-homogeneous model for heat transfer with temperature dependent fluid viscosities. The first model considers one-dimensional fluid flow and two-dimensional heat transfer. The second, more rigorous one is a three-dimensional model for heat transfer and hydrodynamics. The simulation results obtained with both models are in good agreement with experimental results. The experiments have been performed with glass beads as the stationary phase and water as the liquid phase under different boundary conditions. The temparature profiles inside the packed bed have been measured with thermocouples.

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Heat transfer and hydrodynamics in annular chromatography: CFD-simulation and experiments

Bart

Brozio

Herbsthofer

2000

J. of Therm. Sci.

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Heat transfer – a review of 2000 literature

Goldstein

Eckert

Ibele

et al. 2002

International Journal of Heat and Mass Transfer

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Heat Transfer and Hydrodynamics in Preparative Continuous Annular Chromatography (P-CAC)

Cited by 2 publications

References 10 publications

Heat transfer and hydrodynamics in annular chromatography: CFD-simulation and experiments

Heat transfer and hydrodynamics in annular chromatography: CFD-simulation and experiments

Heat transfer – a review of 2000 literature

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