Heating‐induced Bacteriological and Biochemical Modifications in Human Donor Milk After Holder Pasteurisation

Segura, Aránzazu Gómez de; Escuder, Diana; Montilla, Antonia; Bustos, Gerardo; Pallás, Carmen; Fernández, Leónides; Corzo, Nieves; Rodríguez, Juan M.

doi:10.1097/mpg.0b013e318235d50d

Cited by 44 publications

(46 citation statements)

References 48 publications

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“…In all cases, and using different analytical techniques, no significant difference was found before and after HoP [18,19,23,31,54]. The myoinositol levels were not affected by HoP either [31,54], while glucose was found to be increased [17], stable [31] and reduced [54], although all of the reported variations were low.…”

Section: Resultsmentioning

confidence: 95%

The Effect of Holder Pasteurization on Nutrients and Biologically-Active Components in Donor Human Milk: A Review

Moro²,

et al. 2016

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When a mother’s milk is unavailable, the best alternative is donor milk (DM). Milk delivered to Human Milk Banks should be pasteurized in order to inactivate the microbial agents that may be present. Currently, pasteurization, performed at 62.5 °C for 30 min (Holder Pasteurization, HoP), is recommended for this purpose in international guidelines. Several studies have been performed to investigate the effects of HoP on the properties of DM. The present paper has the aim of reviewing the published papers on this topic, and to provide a comparison of the reported variations of biologically-active DM components before and after HoP. This review was performed by searching the MEDLINE, EMBASE, CINHAL and Cochrane Library databases. Studies that clearly identified the HoP parameters and compared the same DM samples, before and after pasteurization, were focused on. A total of 44 articles satisfied the above criteria, and were therefore selected. The findings from the literature report variable results. A possible explanation for this may be the heterogeneity of the test protocols that were applied. Moreover, the present review spans more than five decades, and modern pasteurizers may be able to modify the degradation kinetics for heat-sensitive substances, compared to older ones. Overall, the data indicate that HoP affects several milk components, although it is difficult to quantify the degradation degree. However, clinical practices demonstrate that many beneficial properties of DM still persist after HoP.

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Section: Resultsmentioning

confidence: 95%

The Effect of Holder Pasteurization on Nutrients and Biologically-Active Components in Donor Human Milk: A Review

Moro²,

et al. 2016

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show abstract

“…12–14,46 Numerous MOM components that are thought to contribute to reduced sepsis, chronic lung disease and neurodevelopmental advantage are reduced or absent in DHM, and include: myoinositol, 28,47 antioxidants, 48,49 lactadherin and mucins, 50 growth factors such as insulin-like growth factor, transforming growth factor-β and epidermal growth factor, soluble CD14 and adipokines. 34,51–57 …”

Section: Mom and Dhm: Impact On Potentially Preventable Morbidities Amentioning

confidence: 99%

Donor Human Milk Update: Evidence, Mechanisms, and Priorities for Research and Practice

Meier

Patel

Esquerra-Zwiers

2017

The Journal of Pediatrics

119

153

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“…24,31,39 Even for raw milk expressed by mothers for their hospitalized infants, the benefits of feeding breast milk likely outweigh the risk of bacterial disease. 34,40,41 However, for infants receiving raw milk from an unfamiliar source, this benefit-risk calculation may not hold.…”

Section: Figurementioning

confidence: 99%

Microbial Contamination of Human Milk Purchased Via the Internet

2013

PEDIATRICS

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Heating‐induced Bacteriological and Biochemical Modifications in Human Donor Milk After Holder Pasteurisation

Abstract: Holder pasteurisation led to the destruction of bacteria present initially in donor milk samples, except for some B cereus that did not display a high virulence potential and did not modify significantly the concentration of the compounds analyzed in the present study.

Cited by 44 publications

References 48 publications

The Effect of Holder Pasteurization on Nutrients and Biologically-Active Components in Donor Human Milk: A Review

The Effect of Holder Pasteurization on Nutrients and Biologically-Active Components in Donor Human Milk: A Review

Donor Human Milk Update: Evidence, Mechanisms, and Priorities for Research and Practice

Microbial Contamination of Human Milk Purchased Via the Internet

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