Helicobacter Pylori Infection Among Patients Undergoing Upper Gastrointestinal Endoscopy For Dyspepsia

Abstract

Introduction: Helicobacter pylori is associated with the pathogenicity of gastroduodenal mucosal lesions, ulcers, and gastric cancers. The present study was undertaken to study the prevalence of H. pylori infection among patients undergoing upper gastrointestinal (UGI) endoscopy for dyspepsia in the Nepalese population. Methods: A cross-sectional, hospital-based study was conducted among patients presenting with dyspepsia. Each study patient underwent upper gastrointestinal endoscopy followed by a rapid urease test or histopathology from the biopsy sample for H. pylori detection. Data analysis was done by SPSS 20. Results: The mean age of the patients was 43±11.65 years (M: F=1.4:1) with male predominance. The prevalence of H. pylori infection was 53.2% among the dyspeptic patients undergoing UGI endoscopy. The H. pylori infection was significantly associated with gastritis, duodenitis, gastric ulcer, duodenal ulcer, and gastric cancer (p <0.05). Conclusion: This study demonstrates a high prevalence of H. pylori among patients undergoing UGI endoscopy for dyspepsia.

Prevalence of Helicobacter Pylori Infection in Endoscopic Biopsy Specimen Among Acid Peptic Disorder Patients Attending Gastro-Outpatient Department of a Tertiary Care Center in Central Nepal

“…9 In this study, we found a higher female HP infection status over males unlike similar previous studies. 2,[10][11][12] This discrepancy could have been a result of study population as this current study included a higher number of female patients. On a global scenario, there are conflicting reports regarding gender predisposition to HP infection.…”

“…1 The prevalence of HP has been reported to be around 30-65% using several diagnostic aids among the general Nepalese population. [2][3][4][5] In the present study, we aimed to find the incidence of HP in endoscopic biopsy among patients attending Gastro outpatient department (OPD) of Chitwan Medical College with symptoms of epigastric pain.…”