Hellp, Microangiopathic Hemolytic Anemia, and Preeclampsia

Stratta, Piero; Canavese, Caterina; Vercellone, A

doi:10.3109/10641959309042867

Cited by 7 publications

(4 citation statements)

References 37 publications

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“…Though our understanding of the pathogenic mechanisms involved has improved (8,10), uncertainty regarding diagnosis, management and prognosis persist (12,13).…”

Section: Discussionmentioning

confidence: 98%

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THE HELLP SYNDROME, A PROSPECTIVE STUDY^*

et al. 2001

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“…Though our understanding of the pathogenic mechanisms involved has improved (8,10), uncertainty regarding diagnosis, management and prognosis persist (12,13).…”

Section: Discussionmentioning

confidence: 98%

“…Recent reports show that the HELLP syndrome is the most common cause of acute renal failure in pregnant women (6). Though the etiology is unknown, the underlying pathology is one of thrombotic microangiopathy (7,8).…”

Section: Introductionmentioning

confidence: 99%

THE HELLP SYNDROME, A PROSPECTIVE STUDY^*

et al. 2001

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“…Currently, the pathogenesis of HIP and HELLP syndrome is attributed to vaso-active agents causing endothelial damage and platelet activation [5,7]. It remains unknown whether these agents may affect the fetus.…”

Section: Discussionmentioning

confidence: 99%

Neonatal morbidity and mortality associated with maternal haemolysis elevated liver enzymes and low platelets syndrome

Dötsch¹,

Hohmann

Kühl³

1997

European Journal of Pediatrics

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“…Desde el punto de vista fisiopatológico se explica por una interacción anormal entre la microvasculatura de diferentes órganos y los elementos figurados de la sangre; que a nivel hepático se caracteriza por daño endotelial seguido de activación y agregación plaquetaria, que finalmente resulta en isquemia distal con muerte del hepatocito, esta vasculopatía puede estar limitada en un segmento hepático (necrosis periportal o focal) o difusamente a través de todo el hígado (infarto hepático y hematoma subcapsular) (5)(6)(7)(8). Esto se traduce en alteraciones evidentes del laboratorio hematológi-co como trombocitopenia, anemia hemolítica microangiopática y liberación de productos celulares, particularmente a nivel hepático, incluyendo transaminasas y deshidrogenasa láctica.…”

Section: Introductionunclassified

Síndrome Hellp: Experiencia Del Hospital Regional De Puerto Montt, 2000-2006

Sch

P³

et al. 2008

Rev. chil. obstet. ginecol.

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RESUMENObjetivos: Caracterizar el síndrome HELLP en una población obstétrica de la décima Región de Chile. Método: Análisis de 33 pacientes con síndrome HELLP asistidas en el hospital de Puerto Montt, en el período [2000][2001][2002][2003][2004][2005][2006]. Resultados: La incidencia fue 1,3 casos por mil partos. La edad gestacional promedio de presentación fue de 33 semanas. En 84,8% de las pacientes el diagnóstico fue anteparto. El 27% de las pacientes recibió dexametasona. La principal complicación materna fue la insuficiencia renal aguda. El 91% de las pacientes presentó hipertensión arterial. No hubo muertes maternas. El peso promedio de los recién nacidos fue 2.048 gramos; 42% con edad gestacional menor a 34 semanas; 34,4% pesó menos de 1500 gramos; 9,4% presentó depresión neonatal severa a los 5 minutos; 12,1% falleció en el período neonatal. Conclusiones: El síndrome HELLP es una patología de baja incidencia y con elevada morbimortalidad neonatal. PALABRAS CLAVE: Síndrome HELLP, pronóstico perinatal, dexametasona SUMMARYObjectives: To characterize HELLP syndrome. Method: Analysis of 33 patients with HELLP syndrome assisted at the Puerto Montt hospital, in the period 2000-2006. Results: The incidence was 1.3 cases per thousand births. The average gestational age at presentation was 33 weeks; 84.4% of patient had prepartum diagnosis; 27% of patients received dexamethasone. The main complication was maternal acute renal failure. 91% of patients had hypertension syndrome. There were no maternal deaths. The average weight of newborns was 2,048 grams; 42% with gestational age less than 34 weeks; 34.4% weighed less than 1,500 grams; 9.4% had severe 5 minutes newborn depression; 12.1% died in the neonatal period. Conclusions:The HELLP syndrome is a disease of low incidence, with a high neonatal morbimortality.

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Hellp, Microangiopathic Hemolytic Anemia, and Preeclampsia

Cited by 7 publications

References 37 publications

THE HELLP SYNDROME, A PROSPECTIVE STUDY^*

THE HELLP SYNDROME, A PROSPECTIVE STUDY^*

Neonatal morbidity and mortality associated with maternal haemolysis elevated liver enzymes and low platelets syndrome

Síndrome Hellp: Experiencia Del Hospital Regional De Puerto Montt, 2000-2006

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Hellp, Microangiopathic Hemolytic Anemia, and Preeclampsia

Cited by 7 publications

References 37 publications

THE HELLP SYNDROME, A PROSPECTIVE STUDY*

THE HELLP SYNDROME, A PROSPECTIVE STUDY*

Neonatal morbidity and mortality associated with maternal haemolysis elevated liver enzymes and low platelets syndrome

Síndrome Hellp: Experiencia Del Hospital Regional De Puerto Montt, 2000-2006

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Product

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THE HELLP SYNDROME, A PROSPECTIVE STUDY^*

THE HELLP SYNDROME, A PROSPECTIVE STUDY^*