Hemagglutinating activity of proteins from<i>Parkia speciosa</i>seeds

Chankhamjon, Kanokwan; Petsom, Amorn; Sawasdipuksa, Narumon; Sangvanich, Polkit

doi:10.3109/13880200903046195

Cited by 8 publications

(4 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lectins with mitogenic activity usually exert antiproliferative, immunomodulatory, and antitumor properties [54]. Similar to lectins from other sources, the P. speciosa lectin also had a strong hemagglutinating activity for rabbit, goat, rat, and human erythrocytes [47, 56, 57]. These findings indicate that lectin from the seeds may increase DNA synthesis and, therefore, may enhance immune response against infections and tumors.…”

Section: Properties Of P Speciosamentioning

confidence: 98%

See 1 more Smart Citation

Parkia speciosaHassk.: A Potential Phytomedicine

Kamisah

Othman

Qodriyah

et al. 2013

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Parkia speciosa Hassk., or stink bean, is a plant indigenous to Southeast Asia. It is consumed either raw or cooked. It has been used in folk medicine to treat diabetes, hypertension, and kidney problems. It contains minerals and vitamins. It displays many beneficial properties. Its extracts from the empty pods and seeds have a high content of total polyphenol, phytosterol, and flavonoids. It demonstrates a good antioxidant activity. Its hypoglycemic effect is reported to be attributable to the presence of β-sitosterol, stigmasterol, and stigmast-4-en-3-one. The cyclic polysulfide compounds exhibit antibacterial activity, while thiazolidine-4-carboxylic acid possesses anticancer property. The pharmacological properties of the plant extract are described in this review. With ongoing research conducted on the plant extracts, Parkia speciosa has a potential to be developed as a phytomedicine.

show abstract

Section: Properties Of P Speciosamentioning

confidence: 98%

“…However, the aqueous extract of the plant demonstrated a good α -glucosidase inhibitory activity with the empty pods having almost 15 times higher activity than the seeds [46, 47]. The α -glucosidase inhibitory activity was also observed in the petroleum ether, dichloromethane, and ethanolic extracts.…”

Section: Properties Of P Speciosamentioning

confidence: 99%

Parkia speciosaHassk.: A Potential Phytomedicine

Kamisah

Othman

Qodriyah

et al. 2013

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

show abstract

“…The lectin from P. speciosa seeds has mitogenic activity by stimulating incorporation of [3H] thymidine into DNA of rat thymocytes (Suvachittanont and Jaranchavanapet, 2000). The earlier report also showed that lectin from P. speciosa seed has hemagglutinating activity (Chankhamjon et al, 2010).…”

Section: Discussionmentioning

confidence: 91%

Inhibitory activity of Heinz body induction in vitro antioxidant model and tannin concentration of Thai mimosaceous plant extracts

Tunsaringkarn¹,

Soogarun²,

Rungsiyothin³

et al. 2012

J. Med. Plants Res.

View full text Add to dashboard Cite

Medicinal plants have been used for traditional treatment and known to possess antioxidant activities that may help to reduce the risk of oxidative stress-related diseases. Chemically-induced oxidative hemolysis is usually associated with the formation of Heinz bodies-insoluble precipitates within red blood cells, indicating the oxidative destruction of hemoglobin. In the present study, antioxidant activity was investigated by Heinz body induction in vitro model for providing preliminary data selection of plant extracts compared to tannin concentration in Thai mimosaceous plant extracts. Twenty-one Thai mimosaceous plants, extracted by ethanol, were screened for tannin concentration and antioxidant activity of inhibitory Heinz body induction under in vitro condition. The study showed that the percentage of Heinz body inhibition activity from Parkia speciosa seed coat was the highest and followed by Xylia xylocarpa bark, P. speciosa pericarp, and Entada rheedii seed coat, respectively with inhibition concentration 25 (IC 25) of 2.68, 15.71, and 28.14 mg/ml, respectively. In addition, X. xylocarpa bark, E. rheedii seed coat and P. speciosa Hassk. seed coat also contained high tannin concentration. The percentage of Heinz body inhibition activity from plant extracts at dilution 1: 2 and 1: 10 (50.00 and 10.00 mg/ml) were shown correlation with tannin concentration (p < 0.01, r = 0.658 and p < 0.05, r = 0.536, respectively). This study also found that tannin could be found in all plant extracts and also inhibited the Heinz body induction at the minimum level of 0.625 mg/ml. Mimosaceous plants contained antioxidant activity demonstrated by Heinz body inhibition activity and most of the plant extracts with high Heinz body inhibition activities might be caused by high tannin concentration. This data would be valuable sources for searching potent medicine in the future.

show abstract

“…The Parkia speciosa seed has been shown to be an excellent source of antioxidant and antihypertensive peptides which could be developed as a natural functional food ingredient or novel nutraceutical [16,17]. Several researchers have reported that Parkia speciosa contains crucial medicinal chemicals which exhibit potential biological activities, such as, that of anti-cancer [18], antibacterial [19], antioxidant [20], antiangiogenic [20], antiulcer [21] and showing hemagglutinating activity [22]. Gan et al, evaluated the physico-chemical properties of the polysaccharides extracted from the Parkia speciosa pods [23].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical investigation of amino acids Parkia seeds using the composite electrode based on copper/carbon nanotube/nanodiamond

Babadi

Hosseini

Shavandi

et al. 2019

Journal of Environmental Chemical Engineering

View full text Add to dashboard Cite

An electrochemical biosensor comprising copper, nano-diamond (ND) and carbon nanotube (CNT) has been fabricated to detect the amino acids of Parkia speciosa (PS) seeds. Parkia speciosa (stink bean), a Southeast Asian legume, is composed of medicinal chemicals which exhibit biological activities. The electro-catalytic activity of three electrodes Cu/CNT/ND, Zn/CNT/ND and NiO/CNT/ND was studied using 5 mM potassium ferrocyanide in 0.1 MKCl. The Zn/CNT/ND electrode exhibited irreversible reaction free oxidation with reduction peaks at −1 V, whereas, a pair redox peaks was observed for Cu/CNT/ND electrode. The immobilization of L-amino acid oxidase on the Cu/CNT/ND electrode was carried out to catalyze the amino acids detection. It was observed that the anodic and cathodic peak currents increased linearly with both the square root of the scan rate (ν 1/2 ) and scan rate (ν) over the studied scan range of 0.01-0.1 V/s with high correlation coefficients and following both the adsorption and the diffusion-controlled mechanisms. The developed biosensor displayed a very good electrocatalytic activity toward the oxidation of the amino acid to release H 2 O 2 and NH 3 as a result of the reaction between the active sites and the Parkia speciosa component. This was also confirmed by a drop in the pH value from 6.8 to 6.5 and a change in the color of the solution from green to yellow (releasing H 2 S). The impedance results indicated an inductance behavior due to the co-formation of the hydrogen peroxide (H 2 O 2 ) and the water via the adsorption on the electrode surface.

show abstract

Hemagglutinating activity of proteins fromParkia speciosaseeds

Cited by 8 publications

References 20 publications

Parkia speciosaHassk.: A Potential Phytomedicine

Parkia speciosaHassk.: A Potential Phytomedicine

Inhibitory activity of Heinz body induction in vitro antioxidant model and tannin concentration of Thai mimosaceous plant extracts

Electrochemical investigation of amino acids Parkia seeds using the composite electrode based on copper/carbon nanotube/nanodiamond

Contact Info

Product

Resources

About