Hematological Cytology in Organ Transplantation

Hammer, C.; Lersch, C

doi:10.1007/978-3-642-73097-9_19

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Zerstorungsmechanismen Von Allogenen Transpiantaten1

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1991

1992

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Cited by 2 publications

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“…Durch das sogenannte "Zytoimmunologische Monitoring" (ZIM) konnen lichtmikroskopisch immunkompetente Zellen im peripheren Blut nachgewiesen werden [106]. Dabei ist es moglich, durch die Beriicksichtigung von aktivierten Lymphozyten, Lymphoblasten und "large granular lymphocytes" das Auftreten sowohl von AbstoBungsreaktionen als auch von viralen und bakteriellen Infektionen zu bestimmen [107].…”

Section: Zerstorungsmechanismen Von Allogenen Transpiantatenunclassified

Immunologie vitaler und konservierter Transplantate

Hammer

Bujía

1992

Teil I: Referate

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Section: Zerstorungsmechanismen Von Allogenen Transpiantatenunclassified

Immunologie vitaler und konservierter Transplantate

Hammer

Bujía

1992

Teil I: Referate

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Immunological behavior of preserved human tracheal allografts: Immunological monitoring of a human tracheal recipient

Bujia,

Pitzke,

Krombach

et al. 1991

Clinical Transplantation

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Abstract:The use of preserved tracheal allografting is a discussed method for the reconstruction of tracheal defects. To characterize the systemic and local immunological events following the transplantation of preserved human tracheal allografts, various immunological parameters were measured before and after transplantation in 1 human tracheal transplant recipient. Peripheral mononuclear cells were obtained and prepared for cytological monitoring. Biopsies of the anastomosis region were taken to characterize the histologic changes, as well as the extent and phenotype of cellular infiltrates, as determined by immunoperoxidase labelling. The results were compared with those of another patient who underwent a tracheal resection followed by an end‐to‐end anastomosis. While the biopsies showed a slight inflammatory reaction, signs of systemic immunoactivation were not found. Moreover, the absence of signs of clinical rejection suggests that merthiolate‐preserved human tracheal allografts represent a suitable replacement material for reconstruction of large tracheal defects.

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Hematological Cytology in Organ Transplantation

Cited by 2 publications

References 3 publications

Immunologie vitaler und konservierter Transplantate

Immunologie vitaler und konservierter Transplantate

Immunological behavior of preserved human tracheal allografts: Immunological monitoring of a human tracheal recipient

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