2015
DOI: 10.4314/ajcem.v17i1.4
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Hematological derangement patterns in Nigerian dogs infected with <i>Trypanosoma brucei</i>: A simple prototype for assessing tolerance to trypanosome infections in animals

Abstract: The haematology of Nigerian local puppies experimentally infected with the Federe strain of Trypanosoma brucei was studied in a total of six 9-weeks old puppies born to two local bitches. Four were randomly selected and inoculated with about 0.8 x 10 6 of T .brucei subcutaneously and the remaining two served as the uninfected control. The parasitaemia was monitored daily using wet mount microscopy. The packed cell volume (PCV), red blood cell (RBC) counts, total and differential white blood cell (WBC) counts a… Show more

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Cited by 3 publications
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“…Trypanosomosis is known to alter hematological parameters of infected dogs (Allam et al, 2011). There is usually pancytopenia (Abenga, Ode, Agishi, 2016), associated with immunosuppression and anemia. In the present study, decrease in the leucocyte count was observed 14 d.p.i.…”
Section: Discussionmentioning
confidence: 99%
“…Trypanosomosis is known to alter hematological parameters of infected dogs (Allam et al, 2011). There is usually pancytopenia (Abenga, Ode, Agishi, 2016), associated with immunosuppression and anemia. In the present study, decrease in the leucocyte count was observed 14 d.p.i.…”
Section: Discussionmentioning
confidence: 99%
“…It could also suggest possible immunostimulatory effect of SEC. Anemia is a regular and an important feature of trypanosomosis in animals (Abenga et al, 2016). Trypanosomes cause massive destruction of RBCs and subsequent depletion of the RBC number, severe reduction of the PCV and hemoglobin concentrations.…”
Section: Discussionmentioning
confidence: 99%