Hematological Parameters and Tumor Size in Rectal Cancer

Andronic, Octavian; Bolocan, Alexandra; Radu, Georgiana; Păduraru, D; Ion, Daniel; Oprescu, S

doi:10.33695/jss.v6i2.269

“…The findings of our study are in agreement with those obtained by other investigations (Omar et al, 2016;Zhu et al, 2019;Rojko et al, 2020). Also, having a high number of platelets has been linked to the progression of other cancers, such as rectal cancer (Andronic et al, 2019) and breast cancer (Ali et al, 2020). Platelets play an important role in clotting and inflammation, and stimulated platelets have been related to an increased risk of cancer through a variety of pathways .…”

Section: Resultssupporting

confidence: 93%

Evaluation of some hematological criteria in lung cancer patients

Jasim

¹

,

Hadi

²

2022

ijhs

0

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Lung cancer is one of the most commonly diagnosed diseases in both men and women and the leading cause of cancer-related death worldwide. This study aims to investigate the effect of lung cancer on the role of some hematological criteria in patient serum. There were fifty (50) lung cancer patients (males and females) and forty (40) healthy subjects in the present study. The levels of some hematological parameters that include erythrocyte indices [red blood cell (RBCs) count, hemoglobin (Hb), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), and red cell distribution width (RDW)], leukocyte indices [total white blood cell (WBCs) count, neutrophil percentage (%), lymphocyte percentage (%)], and thrombocyte indices [platelet count and mean platelet volume (MPV)] was recorded. In general, the levels of all hematological criteria in the serum of lung cancer patients were significantly different (p<0.05) from those of the control groups. In conclusion, hematological measurements can provide important prognostic information for patients with lung cancer, and they are simple and readily available at medical centers.

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“…The findings of our study are in agreement with those obtained by other investigations (Omar et al, 2016;Zhu et al, 2019;Rojko et al, 2020). Also, having a high number of platelets has been linked to the progression of other cancers, such as rectal cancer (Andronic et al, 2019) and breast cancer (Ali et al, 2020).…”

Section: Resultssupporting

confidence: 93%

Evaluation of some hematological criteria in lung cancer patients

Jasim

¹

,

Hadi

²

2022

ijhs

0

View full text Add to dashboard Cite

Lung cancer is one of the most commonly diagnosed diseases in both men and women and the leading cause of cancer-related death worldwide. This study aims to investigate the effect of lung cancer on the role of some hematological criteria in patient serum. There were fifty (50) lung cancer patients (males and females) and forty (40) healthy subjects in the present study. The levels of some hematological parameters that include erythrocyte indices [red blood cell (RBCs) count, hemoglobin (Hb), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), and red cell distribution width (RDW)], leukocyte indices [total white blood cell (WBCs) count, neutrophil percentage (%), lymphocyte percentage (%)], and thrombocyte indices [platelet count and mean platelet volume (MPV)] was recorded. In general, the levels of all hematological criteria in the serum of lung cancer patients were significantly different (p<0.05) from those of the control groups. In conclusion, hematological measurements can provide important prognostic information for patients with lung cancer, and they are simple and readily available at medical centers.

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“…One of the important factors that affect survival in colon cancers is the stage of the tumor [9]. Today, the usage of simple, easy-to-apply, cheap and non-invasive tests has become desirable in preop staging of colorectal cancers [10]. The fact that hematological parameters are simple, cheap and easily accessible methods increase their applicability.…”

Section: Discussionmentioning

confidence: 99%

The contribution of hematological parameters to prediction of the phase in stage 2 and stage 3 colon cancers

Karacan¹,

Yılmaz²,

Yıldız³

et al. 2020

J Clin Med Kaz

0

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Colorectal cancers are a significant cause of cancer-related deaths around the world. In the preoperative staging of colon cancers, radiological images and various blood tests are used. However, it is both difficult and expensive to apply radiological examinations. In our study, we aimed at predicting the stage of colon cancers by preoperatively viewing the hematological parameters, which are simple, cheap and easy to apply.Material and methods: The patients, who had been operated due to colon cancer by a single surgeon in the General Surgery Clinic between January 2015 and January 2020, were divided into two groups as stage 2 and stage 3 according to the tumor-nodule-metastases classification. In these groups, preoperative mean platelet volume, carcinoembryonic antigen, platelet/lymphocyte count ratio and neutrophil/lymphocyte count ratios were checked and evaluated in terms of staging and significance according to postoperative pathology results. According to the tumor-nodule-metastases classification, Stage 1-4 patients, emergency cases, patients with an inflammatory disease and rectal cancer were excluded from the study.Results: In the study, 38 of 59 patients who had been operated between January 2015 and January 2020 were found to be at stage 2 (group 1), and 21 patients at stage 3 (group 2). While no significant difference was found between carcinoembryonic antigen and neutrophil/lymphocyte levels between group 1 and group 2, a proportional increase was observed between the increase in platelet/lymphocyte ratio and staging (p=0.041). Mean platelet volume was seen to be proportional to stage progression (p=0.03). Conclusion:We think that platelet/lymphocyte ratio and mean platelet volume levels can easily be applied as a cheap and simple test in the prediction of the preoperative stage in stage 2-3 colon cancers.

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Hematological Parameters and Tumor Size in Rectal Cancer

Cited by 3 publications

References 16 publications

Evaluation of some hematological criteria in lung cancer patients

Evaluation of some hematological criteria in lung cancer patients

Evaluation of some hematological criteria in lung cancer patients

The contribution of hematological parameters to prediction of the phase in stage 2 and stage 3 colon cancers

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