Hemin-doped metal–organic frameworks based nanozyme electrochemical sensor with high stability and sensitivity for dopamine detection

Abstract

Hemin-doped-HKUST-1 nanozyme has been successfully synthesized and used for dopamine detection with excellent reproducibility, stability and anti-interference.

Vein-Like Ni-BTC@Ni3S4 with Sulfur Vacancy and Ni3+ Fabricated In Situ Etching Vulcanization Strategy for an Electrochemical Sensor of Dopamine

“…With the increase in the pH value, the oxidation peak potential had a negative shift, indicating that protons were involved in the electrode reaction . As shown in Figure b, the peak oxidation current of DA reaches its maximum value at pH 7.0, which may be due to the fact that low and high pH values affect the conjugate effect between Ni-BTC@Ni 3 S 4 and DA, resulting in reduced sensitivity . Accordingly, pH 7.0 was the ideal value for subsequent analyses.…”

“…56 As shown in Figure 12b, the peak oxidation current of DA reaches its maximum value at pH 7.0, which may be due to the fact that low and high pH values affect the conjugate effect between Ni-BTC@Ni 3 S 4 and DA, resulting in reduced sensitivity. 57 Accordingly, pH 7.0 was the ideal value for subsequent analyses. In addition, the linear relationship between peak potential E p and pH is shown in Figure 12c, and the linear equation is as follows The slope of this line is −0.0557 V/pH, which is very close to the theoretical value (−0.059 V/pH), indicating that the number of protons and electrons transferred in the electrochemical oxidation process is equal.…”

Recent advancements of metal–organic frameworks in sensing platforms: relevance in the welfare of the environment and the medical sciences with regard to cancer and SARS-CoV-2

“…Small molecules like dopamine, which is a neurotransmitter in the human body, have been detected by MOFs using electrochemical methods. 59 a Dopamine is directly involved in the central nervous system of the human body. 59 b So, any abnormal amount of dopamine in the human body causes cognitive disorders, like Parkinson’s disease, or neurological diseases, like schizophrenia, etc.…”

“…59 a Dopamine is directly involved in the central nervous system of the human body. 59 b So, any abnormal amount of dopamine in the human body causes cognitive disorders, like Parkinson’s disease, or neurological diseases, like schizophrenia, etc. 59 b …”

“…59 b So, any abnormal amount of dopamine in the human body causes cognitive disorders, like Parkinson’s disease, or neurological diseases, like schizophrenia, etc. 59 b …”