Hemodiluição normovolêmica aguda em crianças submetidas a artrodese de coluna vertebral pela via posterior

Oliveira, Gizelda S de; Tenório, Sérgio Bernardo; Cumino, Débora O; Gomes, Daniela B G; Namba, Edson N; Maidana, José Luis A; Rocha, Luiz Eduardo Munhoz da

doi:10.1590/s0034-70942004000100012

Cited by 2 publications

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“…de Oliveira et al 10 also investigated the efficacy of ANH among patients in idiopathic scoliosis and reported a significantly lower rate of allogeneic transfusion in an ANH group (28%) compared to 79% allogeneic blood transfusion in their control group. Their study was performed in patients with idiopathic scoliosis whereas the aetiology in the present study was heterogenous consisting of idiopathic, congenital, post TB, neuromuscular, neurofibromatosis and syndromic aetiologies.…”

Section: Discussionmentioning

confidence: 99%

“…Randomization was continued for 22 months until a total of 45 patients and 31 patients were enrolled into Group1 and Group2, respectively. Using the power and sample size calculating software 12 , we were able to determine that this sample size had adequate statistical power for analysis (alpha=0.05 N=45 , P 0 =0.28 , P 1 =0.79 , M=0.69, Power for uncorrected chi-squared test= .998, where “alpha” is the probability committing a type 1 error, “N” is the number of participants in the ANH groupof the current study, “M” is the ratio of number of participants in the control Groupto ANH group for the current study and P 0 and P 1 are the reported probability of allogeneic transfusion in an ANH group and control group in a previous study 10 , respectively).…”

Section: Methodsmentioning

confidence: 99%

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The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana

Wulff¹,

Duah²,

Oteng-Yeboah

et al. 2021

gmj

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Objectives: To assess the safety and clinical benefits of intraoperative acute normovolaemic haemodilution (ANH) incomplex spine surgery. Design: Prospective comparative cohort studySetting: A private orthopaedic hospital in GhanaPatients: Seventy-six patients who underwent complex spine deformity surgeryInterventions: Patients were randomly assigned to two groups. 45 patients to the acute normovolaemic haemodilution(ANH) or Group 1 and 31patients to the non-ANH or Group 2. Following anesthetic administration and before incision, autologous blood was collected from patients in Group1 and was reinfused during/shortly after surgery while patients in Group2 were transfused with compatible allogeneic blood intraoperatively.Main Outcome Measures: Changes in haemodynamic parameters and incidence of allogeneic transfusions and related complications.Results: The mean age (years), gender ratio, deformity size and aetiology, fusion levels, and operative times were similar in both groups. Blood loss (ml) of patients in groups 1 and 2 were 1583ml± 830.48 vs 1623ml ± 681.34, p=0.82, respectively. The rate of allogeneic blood transfusion in groups 1 and 2 were 71% vs 80.65%, p=0.88, respectively. Haemoglobin levels (g/dL) in groups 1 and 2 were comparable in both groups at Post-operative Day (POD) 0 and POD 1. Incidence of minor allogeneic transfusion reaction was 1/45 vs 1/31, p=0.80, group-1 and group-2, respectively.Conclusion: Acute normovolaemic haemodilution can be safely performed in complex spine surgery in underserved regions. However, its use does not obviate allogeneic transfusion in patients with complex spine deformities in whom large volumes of blood loss is expected.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana

Wulff¹,

Duah²,

Oteng-Yeboah

et al. 2021

gmj

View full text Add to dashboard Cite

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Hemodiluição normovolêmica aguda em cirurgias de deformidade da coluna

et al. 2019

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Objective To prospectively compare the clinical and laboratorial aspects of patients undergoing spine deformity surgery, using the acute normovolemic hemodilution technique with tranexamic acid, versus a control group with tranexamic acid alone, and to evaluate the influence of hemodilution in intraoperative bleeding and the need for homologous transfusion. Materials and Methods Comparative prospective study with patients aged between 12 and 65 years undergoing spine deformity surgery with the acute normovolemic hemodilution technique associated with tranexamic acid versus a control group to which only tranexamic acid (15 mg/kg) was administered. Laboratorial exams were performed and analyzed in three different moments. Results A total of 30 patients were included in the present study: 17 in the hemodilution group, and 13 in the control group. The mean duration of the surgery in the hemodilution group was longer. The number of levels submitted to surgery ranged from 7 to 16 in the hemodilution group, and from 4 to 13 in the control group. Osteotomy, predominantly of the posterior kind, was performed in 20 patients. There was more intraoperative bleeding in the control group. All patients were stable during the procedures. Only 6 participants needed homologous blood transfusion, mostly from the control group ( p > 0.05). Conclusion There was no significant difference between the two groups regarding the need for blood transfusion and intraoperative bleeding. The severity of the deformity was the main determinant for homologous blood transfusion.

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Hemodiluição normovolêmica aguda em crianças submetidas a artrodese de coluna vertebral pela via posterior

Abstract: RESUMO S foram, respectivamente, 7,56 ± 3,203 dias e 9,75 ± 4,245 dias (p = 0,009

Cited by 2 publications

References 14 publications

The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana

The efficacy and safety of intraoperative acute normovolaemic haemodilution in complex spine surgery in a private surgical facility in Ghana

Hemodiluição normovolêmica aguda em cirurgias de deformidade da coluna

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