Hemodynamics During Hemodialysis, Sequential Ultrafiltration and Hemofiltration

Hampl, H.; Paeprer, H; Unger, Volker; Kessel, Michael

doi:10.3109/08860227909064912

Cited by 63 publications

(33 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results are in accordance with invasive hemodynamic studies of hypotension during hemodialysis." The hemodynamic responses to ultrafiltration differ from those following dialysis; 31 …”

Section: 02) With Changes In Total Peripheral Resistance (Atpr Grapmentioning

confidence: 99%

Blood pressure response to hemodialysis.

Chaignon¹,

Chen²,

Tarazi³

et al. 1981

Hypertension

View full text Add to dashboard Cite

SUMMARY Blood pressure response to hemodialysis was investigated in IS patients with end-stage kidney disease; mean arterial pressure was unchanged in fire (Group 1) and reduced 10 mm Hg in 10 (Group 2). The two groups did not differ significantly with regard to either biochemical rallies or hemodynamic indices before dialysis, and both sustained comparable reduction in body weight, total blood volume, and cardiac output following dialysis. Heart rate remained unchanged In both. The only significant difference between the two was the response of total peripheral resistance (TPR) to fluid depletion. TPR rose adequately in Group 1 but was unchanged in Group 2 (7.5 ± 2.2 (SE) VS 0.7 ± 1.1 units, p < 0.02S) despite equal fall in cardiac output in both (881 ± 212 vs 890 ± 173 ral/m, p > 0.10). Thus, differences in arterial pressure response to fluid loss by hemodialysis could be due to impaired autonomic control of resistance vessels; this abnormality might not be revealed by tests of baroreceptor activity that depend only on heart rate responses to blood pressure variations. UREMIC patients frequently present difficulties in management during hemodialysis, particularly because of severe hypotension in some patients. This has been related either to the magnitude of fluid loss or to the autonomic neuropathy that has been reported in renal insufficiency.

show abstract

Section: 02) With Changes In Total Peripheral Resistance (Atpr Grapmentioning

confidence: 99%

Blood pressure response to hemodialysis.

Chaignon¹,

Chen²,

Tarazi³

et al. 1981

Hypertension

View full text Add to dashboard Cite

show abstract

“…Since blood was purified at first in both methods, the circulating blood com partment was affected most. It is well known that the circulating blood volume decreases during both methods [3,5]. The change in serum protein concentration was measured in a separate experiment to estimate the change in circulating blood volume [5], A solid decrease in circulating blood volume was found in both methods, but the change was greater in HD.…”

Section: Discussionmentioning

confidence: 99%

“…This may explain the following merits re ported on HF: the decrease of blood osmolal ity is less [5]; the decrease of circulating blood volume is less, and the asymptomatic re moval of excess body fluid is possible [3][4][5][6], Recently, Shaldon et al [6] reported the rela tionship between sodium flux in HD and HF. They concluded that, although the urea filtra tion rate and urea clearance were higher in HF than HD to compensate for shorter treat ment time, significantly less hypotension de veloped owing to sodium flux in HF.…”

Section: Discussionmentioning

confidence: 99%

“…It is generally agreed that a smaller mor bidity and a smaller incidence of dialysis dis equilibrium syndrome are found during he mofiltration (HF) as compared with hemo dialysis (HD) [1][2][3][4][5][6]. Accordingly, easy and asymptomatic removal of excess body fluid is possible by HF, leading to better control of hypertensive as well as hypotensive patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparative Studies between Hemofiltration and Hemodialysis on Urea and Isotope-Labelled Sodium Kinetics

et al. 1983

View full text Add to dashboard Cite

Comparative studies on urea and sodium kinetics were performed between hemodialysis (HD) and hemofiltration (HF). 10 patients on HF were examined and 11 patients on HD were then selected to match the HF group on the basis of age, body weight and height. The urea concentration of serum, cerebrospinal fluid (CSF) and total urea removed were measured during HD and HF. The slope of regression line of the serum urea concentration during the 5 h of treatment was significantly higher for HD, while the total urea removed was comparable between the two. On the contrary, CSF reduction in urea was significantly greater after HF, resulting in a smaller urea concentration gradient between serum and CSF. The sodium kinetics during the procedures were estimated using ²²Na. Although the total ²²Na removed was significantly larger in HF than in HD and body weight loss was comparable between the two groups, the slope of regression line for ²²Na was significantly less with HF whereas total serum Na levels for HF equaled HD. The above results indicate that urea and sodium equilibrated more efficiently between the compartments of body fluid in HF. This resulted in a smaller decrease in osmolality as well as in solute concentration gradients between plasma and CSF.

show abstract

“…The mechanism by which hemofiltration achieves this improved vascular stability has been investigated by numerous authors [19][20][21][22][23] and all report an increase in peripheral resistance as the mechanism by which the blood pressure is maintained ( fig. 3).…”

mentioning

confidence: 99%

Of Sodium, Symptomatology and Syllogism

Shaldon¹,

Baldamus²,

Koch

et al. 1983

Blood Purif

View full text Add to dashboard Cite

Symptomatic intratreatment tolerance of patients to hemofiltration as found to be quantitatively superior to their tolerance to equivalent dialysis in both acute and chronic treatment series at matched sodium ion transport. These results refute an earlier speculative hypothesis that the better vascular stability during hemofiltration compared to hemodialysis is an artifact due to purportedly higher sodium transport during postdilution hemofiltration. In fact, corollary studies of catecholamine levels during matched hemofiltration and hemodialysis suggest that the improved tolerance to hemofiltration was a consequence of better maintained vasoconstrictive activity.

show abstract

Hemodynamics During Hemodialysis, Sequential Ultrafiltration and Hemofiltration

Cited by 63 publications

References 9 publications

Blood pressure response to hemodialysis.

Blood pressure response to hemodialysis.

Comparative Studies between Hemofiltration and Hemodialysis on Urea and Isotope-Labelled Sodium Kinetics

Of Sodium, Symptomatology and Syllogism

Contact Info

Product

Resources

About