Hemoglobin O-Padova or<sub>α2</sub>30(B11)GLU→LYS<sub>β2</sub>Observed in Members of a Turkish Family

Kılınç, Yurdanur; Masunaga, Kumi; Gürgey, Aytemiz; Altay, C; Webber, B. B.; Wilson, J. B.; Kutlar, Abdullah; Huisman, T. H. J.

doi:10.3109/03630268508997044

Cited by 3 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hemoglobinopathies are one of the most serious health problems in our country as well as in the world. According to the screening studies conducted in the Turkish population, the incidence of abnormal hemoglobin has been reported as 0.6-13% (15)(16)(17). The region where hemoglo-binopathies are the most common in our country is the Mediterranean region, the South of Turkey.…”

Section: Discussionmentioning

confidence: 97%

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

Oğuz

Eren

2022

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

View full text Add to dashboard Cite

Objective: Hemoglobin disorders are one of the most common hereditary diseases in the world. In this study, we aimed to evaluate the hemoglobin variants detected by hemoglobin electrophoresis for a three years period in a tertiary care center. Materials and Methods: Hemoglobin variant analysis results of 4804 different variants for a three years period were evaluated retrospectively. Hemoglobin variant analysis was performed by capillary electrophoresis method on Minicap Flex Piercing analyzer (Sebia, Lisses, France). Results: One thousand and six (20.94%) of hemoglobin variants were detected in the study. The number of the patients with thalassemia trait was 1028 (21.39%) and the number of the patients with Beta thalassemia major was 44 (0.91%). In the study, the most common hemoglobin variant was found to be HbF (45.72%). The other hemoglobin variants in decreasing order were HbD, HbS, HbE, HbC and HbH. Conclusion: The place where the study was conducted is not the region where hemoglobinopathy is most commonly known in our country. However, the outcomes of the study indicated different results than expected. It should be noted that the frequency of hemoglobinopathy and the regions where it is seen frequently may change due to the migration wave that occurs due to reasons such as sociocultural, economic and war conditions.

show abstract

Section: Discussionmentioning

confidence: 97%

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

Oğuz

Eren

2022

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

View full text Add to dashboard Cite

show abstract

Comparative evaluation of three assay systems for automated determination of hemoglobin A1c

Halwachs‐Baumann¹,

Katzensteiner²,

Schnedl³

et al. 1997

Clinical Chemistry

View full text Add to dashboard Cite

We evaluated three newly introduced systems for automated determinations of hemoglobin (Hb) A1c, which allow the processing of large amounts of samples in a routine clinical laboratory. We compared these methods—the Variant HPLC, the Hi-Auto A1c analyzer system, and the Roche immunoassay—with the Diamat HPLC system. All showed good precision and good concordance with the Diamat HPLC. The reference range for Hb A1c has to be determined by the laboratory for each assay system. Interference study showed no statistically significant influence of anemia, polycythemia, rheumatoid factor, or chronic hemodialysis, although individual Hb A1c values can be influenced by polycythemia (when measured with the Hi-Auto A1c analyzer) and by chronic hemodialysis (when measured with the Variant HPLC). HPLC was not suitable for measuring Hb A1c in the examined cases of hemoglobin variants; assaying fructosamine seems to be better for monitoring these patients.

show abstract

Haemoglobin O Padova and falsely low haemoglobin A1c in a patient with type I diabetes.

Schnedl

Reisinger

Katzensteiner

et al. 1997

Journal of Clinical Pathology

View full text Add to dashboard Cite

show abstract

Hemoglobin O-Padova or_α230(B11)GLU→LYS_β2Observed in Members of a Turkish Family

Cited by 3 publications

References 4 publications

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

Comparative evaluation of three assay systems for automated determination of hemoglobin A1c

Haemoglobin O Padova and falsely low haemoglobin A1c in a patient with type I diabetes.

Contact Info

Product

Resources

About

Hemoglobin O-Padova orα230(B11)GLU→LYSβ2Observed in Members of a Turkish Family

Cited by 3 publications

References 4 publications

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

The Evaluation of Tertiary Care Center Hemoglobin Variant Data for Three Years Period

Comparative evaluation of three assay systems for automated determination of hemoglobin A1c

Haemoglobin O Padova and falsely low haemoglobin A1c in a patient with type I diabetes.

Contact Info

Product

Resources

About

Hemoglobin O-Padova or_α230(B11)GLU→LYS_β2Observed in Members of a Turkish Family