Hemostatic and Wound Healing Properties of<i>Chromolaena odorata</i>Leaf Extract

Pandith, Hataichanok; Zhang, Xiaobo; Liggett, Jason L.; Min, Kyung‐Won; Gritsanapan, Wandee; Baek, Seung Joon

doi:10.1155/2013/168269

Cited by 42 publications

(29 citation statements)

References 24 publications

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“…Korth.antioxidant and antibacterial activities [87], anti-inflammatory and antinociceptive activities [88] Rhinacanthus nasutus (L.) Kurzantimicrobial activity [89], antiallergic activity [90], antifungal and anti-inflammatory activities [91] Senna alata (L. ) Roxb.antiallergic activity [92], antifungal activity [93] Senna tora (L. ) Roxb.antioxidant and antibacterial activities [94] antibacterial activity Stemona tuberosa Lour.antibacterial activity [95]- burns, skin swellingbland Aloe vera (L.) Burn. f.antioxidant and anti-inflammatory activities [96] wound healing property [97]- stop bleedingnauseating Chromolaena odoratum (L.) R. M. King & H. Roxb.hemostatic and wound healing properties [98]Respiratory system- eliminates sputum, cough,sour Abrus precatorius L.anti-inflammatory and antiallergic activity [99]sore throat Albizia myriophylla Benth.antibacterial activity [100] Phyllanthus emblica L.anti-inflammatory activity [101], anti-Coxsackie Virus B3 [102] Tamarindus indica L.antimicrobial activity [103]bitter Solanum trilobatum L.antimicrobial activity [104], anti-inflammatory and analgesic activities [105]Female problemsfat Sida rhombifolia L.antinociceptive and anti-inflammatory activities [106]Nephrological system- diureticbland Orthosiphon aristatus (Blume) Miq.canti-inflammatory activity [107] Pluchea indica (L. ) Less.anti-inflammatory activity [108], antimicrobial activity [109]…”

Section: Resultsmentioning

confidence: 99%

Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand

Maneenoon

Khuniad

Teanuan

et al. 2015

J Ethnobiology Ethnomedicine

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BackgroundIn rural communities of Thailand, traditional healers still play an important role in local health care systems even though modern medicine is easily accessible. Meanwhile, natural forests in Thailand which are important sources of materia medica are being greatly destroyed. This has led to an erosion of traditional Thai medicine. Furthermore, the concept of medicinal plant selection as medicine based on their tastes is still an important component of traditional Thai medicine, but no or little publications have been reported. Thus the aim of the present study is to collect ethnomedicinal data, medicinal plant tastes and relevant information from experienced traditional healers before they are lost.MethodsAn ethnobotanical survey was carried out to collect information from nine experienced traditional healers on the utilization of medicinal plants in Phatthalung Province, Peninsular Thailand. Data were obtained using semi-structured interviews and participant observations. Plant specimens were also collected and identified according to the plant taxonomic method.ResultsA total of 151 medicinal plants were documented and 98 of these are reported in the study. Local names, medicinal uses, parts used, modes of preparation, and the relationship between ailments and tastes of medicinal plant species are presented.ConclusionsThis research suggests that traditional healers are still considered important for public health among Thai communities and that many people trust the healing properties of medicinal plants. In the future, it is hoped that traditional Thai medicine will be promoted and therefore will help reduce national public health expense.

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Section: Resultsmentioning

confidence: 99%

Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand

Maneenoon

Khuniad

Teanuan

et al. 2015

J Ethnobiology Ethnomedicine

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“…Chromolaena odorata, also known as "Siam weed", is a rapidly growing perennial herb native to Americas mainly Central and South America. The fresh leaves of C. odorata has been used traditionally to stop bleeding, as an anti-inflammatory and wound healing agent (43). Flavonoids, phenolics, tannins, saponins, terpenoides and alkaloids are the main phytochemicals of this plant.…”

Section: Brownea Grandiceps Jacq (Fabaceae)mentioning

confidence: 99%

Medicinal Plants as Potential Hemostatic Agents

et al. 2020

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Purpose: Medicinal plants with a variety of phytochemical ingredients remain a potential source for new drug discovery. The use of medicinal herbs in a wide range of diseases and symptoms, such as bleeding, is prevalent in traditional and ethno medicine worldwide. Thus, this work provides a comprehensive review of medicinal plants or their isolated compounds, with respect to their ethno-medicinal use, which have demonstrated the stimulating effect on the hemostasis process. Methods: The relevant studies were withdrawn from electronic databases including Pubmed, EMBASE and Web of Science with a structured search methodology. Results: The total of 17 medicinal plants with hemostatic activity were extracted. The most frequently studied plant families were Compositae, Lamiaceae, Fabaceae, and Asteraceae. Bioactive compounds exerting hemostatic activity included tannins, iridoid glycosides, glycoconjugate, lignan, saponins and phenolic compounds. The most attributed mechanisms include coagulation stimulation via increasing the factor XII activity and plasma fibrinogen levels, the fibrinolysis inhibition, vascular or smooth muscle constriction and platelet aggregation. The most important adverse effects of high dose extract or isolated compounds administration were hepatotoxicity and nephrotoxicity. Conclusion: This review provides a list of medicinal plants with hemostatic activity that could be used as valuable sources of new plant-based hemostatic agents. Furthermore, this could be practical in detecting possible interactions of plants with anticoagulant, antiplatelet, fibrinolytic and antifibrinolytic medications. __________________________________________________________________________________________

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“…23 The proximate composition and phytochemical contents as well as the medicinal usefulness of the herb have been reported elsewhere. 23,24,25,26 Buccholzia coriacea, commonly called 'Wonderful Kola' , is frequently used in traditional medicine practice. 27 The phytochemical contents and proximate composition as well as the medicinal usefulness of B. coriacea have been reported elsewhere.…”

Section: Introductionmentioning

confidence: 99%

Functional Assessments and Histopathology of Hepatorenal Tissues of Wistar Rats Infused with Carbon Tetrachloride and Treated with Raw and Hydrothermal Processed Herbs

Ojiako¹,

Chikezie²,

Ukairo³

et al. 2017

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Background and Aim: Herbal remedies offer another strategy for alleviation of co-existing liver and kidney pathologic conditions. Objective: The present study ascertained the functional integrity of hepatic and renal tissues, concurrently with blood lipid patterns, of Wistar rats infused with CCl 4 and treated with raw and hydrothermal processed herbs, namely, Monodora myristica, Chromolaena odorata, Buccholzia coriacea and Sphenostylis stenocarpa. Materials and Methods: Measurement of phytochemical contents of the herbs was according to standard methods. The rats were randomly designated on the basis of diets and treatments received for 28 consecutive days. Fibrosis was induced in the Wistar rats by single dose intra-peritoneal injection of CCl 4 for 2 consecutive days. Liver and kidney function tests and serum lipid profile were measured using spectrophotometric methods. Renal and hepatic tissues were subjected to histopathological examinations. Results: The concentrations of alkaloids in the four herbal extracts were within the range of 4.83 ± 0.03 -31.33 ± 0.29 mg/100 g sample, whereas the concentrations of saponins varied within a relatively narrow range: 0.33 ± 0.09 -4.33 ± 0.02 mg/100 g dry sample; p > 0.05. The activity ratios of AST to ALT of the rat groups were generally less than 1.0 unit. Atherogenic indices of fibrotic rats were within the following ranges: TAG/HDL-C ratio (3.59 ± 0.03 -6.76 ± 0.06), TC/HDL-C ratio (3.72 ± 0.02 -6.94 ± 0.05) and LDL-C/HDL-C ratio (2.00 ± 0.01 -4.59 ± 0.02). Conclusion: Losses in phytochemical contents following hydrothermal processing of the herbs did not substantially affect their overall therapeutic scores against morphological and functional impairments of hepatic and renal tissues following CCl 4 intoxication of the rats.

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Hemostatic and Wound Healing Properties ofChromolaena odorataLeaf Extract

Cited by 42 publications

References 24 publications

Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand

Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand

Medicinal Plants as Potential Hemostatic Agents

Functional Assessments and Histopathology of Hepatorenal Tissues of Wistar Rats Infused with Carbon Tetrachloride and Treated with Raw and Hydrothermal Processed Herbs

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