Hemovigilance in France

Hervé, P.; Floris, Michel; Rebibo, Danielle; Morei, Pascal; Andreu, G.

doi:10.1590/s1516-84842000000300003

Cited by 9 publications

(10 citation statements)

References 4 publications

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“…Despite substantial improvement in the safety of blood transfusions, sepsis and death caused by transfusion of red cell (RBC) units contaminated with bacteria continues to be a concern in transfusion medicine 1,2 . Each year, nearly 14 million RBC units are transfused in the United States, of which an estimated 1 in 31,000 to less than 1 per 1 million RBC units may be bacterially contaminated 2,3 .…”

mentioning

confidence: 99%

“…Bacteria found in transfusion‐associated sepsis with RBC units have involved psychrophiles, which are capable of growth at temperatures of 1 to 4°C for up to 42 days and have been found to proliferate at low temperatures to more than 10 5 CFUs per mL 1,5‐9 . Yersinia enterocolitica is the most frequently implicated psychrophilic organism with 21 transfusion‐related cases reported between 1987 and 1997, of which 12 resulted in fatality 5‐7,9 .…”

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confidence: 99%

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Detection of bacteria in stored red cell products using a culture‐based bacterial detection system

Chen

Holme

et al. 2008

Transfusion

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With incubation of eBDS pouches for 48 and 72 hours, 100 percent detection was obtained in 884 samples with bacterial levels of at least 1 CFU per mL, and no false-positive samples were obtained. Based on the bacterial growth patterns, RBC units may be sampled 1 to 3 days after collection for optimal efficacy and read after 48 to 72 hours of incubation of the eBDS sample pouches at 35 degrees C. The Pall eBDS is suited for detection of typical bacterial contaminants in fresh and stored RBCs.

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confidence: 99%

mentioning

confidence: 99%

Detection of bacteria in stored red cell products using a culture‐based bacterial detection system

Chen

Holme

et al. 2008

Transfusion

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“…Hemovigilance is a relatively new procedure in the world, initially implemented in France in 1993 and then in the United Kingdom (10,11) . In Brazil, hemovigilance started in 2004 following the norms of resolution DRC 153-3.…”

Section: Introductionmentioning

confidence: 99%

The importance of hemovigilance in the transmission of infectious diseases

Martins

Barbosa

et al. 2013

Revista Brasileira De Hematologia E Hemoterapia

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BackgroundHemovigilance is an organized system of surveillance throughout the transfusion chain intended to evaluate information in order to prevent the appearance or recurrence of adverse reactions related to the use of blood products. ObjectiveThe aims of this study were to assess the late reporting of incidents related to possible seroconversion in respect to age, marital status and ethnical background, annual variations in late reporting, the number of reports opened and closed, seroconversion of donors and transfusions of blood products within the window period. MethodsThis retrospective, descriptive study used data on blood donations in the blood bank in Uberaba during the period from 2004 to 2011. Some socio-epidemiological characteristics of the donors and serology test results of donors and recipients were analyzed in respect to the late reporting of incidents related to possible seroconversion. The Chi-square test, odds ratio and a regression model were used for statistical analysis. ResultsFrom 2004 to 2011, the blood bank in Uberaba collected 117,857 blood bags, 284 (0.24%) of which were investigated for late reported incidents. The profile of the donors was less than 29 years old, unmarried and non-Whites. Differences in age (p-value < 0.0001), marital status (p-value = 0.0002) and ethnical background (p-value < 0.0001) were found to be statistically significant. There was no statistical difference between men and women (0.24% and 0.23% respectively; p-value = 0.951). The number of late reported incidents increased until 2008 followed by a downward trend until 2011. There were twelve cases of seroconversion in subsequent donations (seven human immunodeficiency virus, four hepatitis B and one hepatitis C) with proven human immunodeficiency virus infection after screening of only one recipient. ConclusionThe twelve cases of seroconversion in donors with subsequent infection proven in one recipient underscores the importance of this tool to increase transfusion safety.

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Section: Introductionmentioning

confidence: 99%

“…Internationally, TSO programs have been in existence since the 1990s with the development of formal hemovigilance programs in many European countries, starting with France in 1993. 3 Unlike the United States, international TSO programs are funded as part of national health care programs. Because the TSO program is government mandated in such situations, the TSO can be located within a hospital or housed as a separate entity within governmental agencies.…”

Section: Introductionmentioning

confidence: 99%

Transfusion safety: is this the business of blood centers?

2011

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ATSO is in a unique position to break down organizational silos between hospitals and blood centers through the development of a collaborative relationship between the two entities. Use of the TSO as blood center staff centralizes the role into a consultative position thereby retaining the independence of the hospitals. The TSO position then becomes a value-added service offered by the blood center designed to supplement processes within the hospital.Whether the TSO is based in the hospital or the blood center, improvements are gained through appropriate utilization of blood components, reductions in hospital costs, ongoing education of hospital staff involved in transfusion practice, and increased availability of blood products within the community. Implementation and standardization of best practice processes for ordering and administration of blood products developed by TSOs leads to improved patient outcomes. As a liaison between hospitals and blood centers, the TSO integrates the mutual goal of transfusion safety: the provision of the safest blood product to the right patient at the right time for the right reason.

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Hemovigilance in France

Abstract: In this work the organization of the hemovigilance system in France, the alert system related to undesirable transfusion effects and the search for seropositive blood donors is discussed. Rev.bras.hematol.hemoter., 2000(22) (3): 368-373

Cited by 9 publications

References 4 publications

Detection of bacteria in stored red cell products using a culture‐based bacterial detection system

Detection of bacteria in stored red cell products using a culture‐based bacterial detection system

The importance of hemovigilance in the transmission of infectious diseases

Transfusion safety: is this the business of blood centers?

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