Henoch Schönlein purpuralı hastalarda epidemiyolojik, klinik ve laboratuvar bulguların değerlendirilmesi

Akça, Ünal

doi:10.15511/tahd.20.00287

Cited by 2 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kaku et al (25) stated that severe joint involvement with arthritis affects renal involvement and prognosis. In the study conducted by Akça et al, renal involvement was found in 51% of the patients with severe joint involvement (26). In our study, mild joint involvement was observed in 61 cases (82.4%) at the onset of the disease, and severe joint involvement was observed in six cases (8.1%).…”

Section: Discussionsupporting

confidence: 58%

The Relationship Between Initial Clinical Findings and Renal Involvement of Henoch Schönlein Purpura in Pediatric Patients

Çavuşoğlu,

Yıldırımer,

Kanık

et al. 2023

Kocatepe Tıp Dergisi

View full text Add to dashboard Cite

OBJECTIVE: Henoch-Schönlein purpura (HSP) is an IgA-associated systemic vasculitis characterized by three important clinical signs of non-thrombocytopenic palpable purpura, abdominal pain, and arthritis. Renal involvement generally determines the prognosis. In this study, it was aimed to determine the relationship between skin, gastrointestinal system (GIS), the severity of joint and renal involvement on the clinical features of children who were followed up with the diagnosis of HSP. MATERIAL AND METHODS: In this prospective cross-sectional study, 74 pediatric patients followed up between January 2011 and January 2012 were evaluated with their history, physical examination, laboratory measurements, treatment received during follow-up, and response to treatment. System involvement of the patients was classified as skin, renal, GIS, and joint involvement. RESULTS: It was determined that 45.9% of the cases were female and 54.1% were male. A significant correlation was found between the severity of arthritis and renal involvement in the first month (p<0.05). There was a significant correlation between the severity of abdominal pain and renal involvement at the time of admission, and also the severity of abdominal pain and severity of renal involvement at the sixth month (p<0.05). A significant correlation was found between the response of abdominal pain to painkillers and renal involvement in the first month (p<0.05). CONCLUSIONS: Severe joint and GIS involvement at the beginning of the disease and severe GIS involvement at the beginning were found to be associated with severe renal involvement in the first and sixth months. Patients who initially had severe abdominal pain, and therefore could not move at all, fall behind from the game, prefer to lie down continuously, and/or those with melena should be evaluated more carefully in terms of renal involvement.

show abstract

Section: Discussionsupporting

confidence: 58%

The Relationship Between Initial Clinical Findings and Renal Involvement of Henoch Schönlein Purpura in Pediatric Patients

Çavuşoğlu,

Yıldırımer,

Kanık

et al. 2023

Kocatepe Tıp Dergisi

View full text Add to dashboard Cite

show abstract

“…It is reported that the platelet count may be normal or high 4,16 . Ece et al and Akça et al detected thrombocytosis in 32.5% and 28.8% of their patients, respectively 17,18 . In our study, the platelet count was higher in the active phase compared to both the remission phase and the control group.…”

Section: Discussionmentioning

confidence: 86%

The Relationship Between IgA Vasculitis and Antioxidant Activity In Children

Temel

2021

Dicle Tıp Dergisi

View full text Add to dashboard Cite

Objective: Immunoglobulin A vasculitis (IgAV) is the most common systemic vasculitis seen in children. The aim of this study is to investigate the relationship between malondialdehyde-induced oxidative stress, antioxidant system and organ involvement in IgAV patients.Method: 32 patients and 28 healthy children were included in the study. Serum malondialdehyde, reduced glutathione, vitamin E, vitamin C, retinol, and beta-carotene levels were measured in patients (separately in both the active and remission phases) and healthy children.Results: MDA levels were significantly higher in patients with active phase while reduced glutathione and vitamin C levels were markedly lower in both the active and the remission phases. Retinol and beta-carotene levels were lower in the active phase. It was found that retinol levels were significantly lower in patients with gastrointestinal system involvement compared to those without. Vitamin C levels were significantly lower in those with kidney involvement compared to those without. Also, a negative correlation was observed between retinol levels and the number of organs involved. Conclusion:We consider that especially vitamin C and vitamin A may be used in the treatment of IgAV. However, whether the derangements of the oxidant/antioxidant balance in the direction of increased oxidative stress are consequences or causes of the events occurring in the active phase of IgAV are open to further investigation.

show abstract

Henoch Schönlein purpuralı hastalarda epidemiyolojik, klinik ve laboratuvar bulguların değerlendirilmesi

Cited by 2 publications

References 17 publications

The Relationship Between Initial Clinical Findings and Renal Involvement of Henoch Schönlein Purpura in Pediatric Patients

The Relationship Between Initial Clinical Findings and Renal Involvement of Henoch Schönlein Purpura in Pediatric Patients

The Relationship Between IgA Vasculitis and Antioxidant Activity In Children

Contact Info

Product

Resources

About