Hepatic calcification following umbilical vein catheterization in a premature baby

Catheter‐related vessel wall calcification detected on point‐of‐care ultrasound

“…1 Venous calcification is also a critical complication because it can require surgical removal of the catheter and may cause other complications due to intimal injury. 2 In the present case, the catheter was successfully removed surgically. Whenever difficulty in PICC removal is encountered, the options are manual removal, surgical removal, or catheter intervention.…”

“…The PICC is widely used in pediatric patients, in whom the rate of complications associated with its use ranges from 20% to 50%, with most of the complications being related to catheter occlusion, catheter dislodgement or infection . Venous calcification is also a critical complication because it can require surgical removal of the catheter and may cause other complications due to intimal injury . In the present case, the catheter was successfully removed surgically.…”

Hepatic Calcified Tumor-like Mass Complicating Umbilical Vein Catheterization in a Neonate

“…Umbilical vein catheterization, commonly implemented among premature neonates for provision of TPN, may be complicated by calcification. 1,2 There have been numerous observations in the radiology literature of calcified lesions detected by imaging in this context. The pathogenesis is considered to involve catheter-induced vascular intimal injury (which may occur even with clinically uncomplicated catheter placement), followed by thrombosis, propagation of the thrombus into the portal vein/ ductus venosus system, and organization/dystrophic calcification.…”

“…A calcified space-occupying lesion, while evoking a broad differential diagnosis, may also be iatrogenic, as a result of umbilical vein catheterization. 1,2 This phenomenon, while well recognized among radiologists, has not been described in the pathology literature. Herein, we describe a case of a hepatic calcified mass complicating umbilical vein catheterization in a neonate and diagnosed by wedge biopsy.…”

Sporotrichoid-like calcinosis cutis and calcifications in vessel walls and eccrine sweat glands following intravenous infusion of calcium gluconate

“…Although vascular calcification following intravenous infusion of calcium-rich solutions has previously been reported in two neonates, 6,7 it was not accompanied with calcinosis cutis. This is the first case of calcifications in vessel walls and eccrine sweat glands accompanied by calcinosis cutis following calcium infusion.…”