Hepatic infarction in preeclampsia as part of the HELLP syndrome: CT appearance

Zissin, Rivka; Yaffe, Daniel; Fejgin, Moshe D.; Olsfanger, D; Shapiro-Feinberg, Myra

doi:10.1007/s002619900571

Cited by 43 publications

(27 citation statements)

References 7 publications

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“…Fetal mortality can reach up to 60 to 86% (2). Imaging manifestations of hepatic rupture, associated with HELLP syndrome, have been described in the literature (3,4). We recently obtained successful clinical outcome after embolization of the hepatic artery and right inferior phrenic artery as the first treatment in a pregnant patient with HELLP syndrome causing hepatic rupture and hemoperitoneum.…”

Section: Introductionmentioning

confidence: 82%

Hepatic Rupture Caused by Hemolysis, Elevated Liver Enzyme, and Low Platelet Count Syndrome: A Case Report with Computed Tomographic and Conventional Angiographic Findings

Lee

Ahn

Choi

et al. 2013

J Korean Soc Radiol

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Section: Introductionmentioning

confidence: 82%

Hepatic Rupture Caused by Hemolysis, Elevated Liver Enzyme, and Low Platelet Count Syndrome: A Case Report with Computed Tomographic and Conventional Angiographic Findings

Lee

Ahn

Choi

et al. 2013

J Korean Soc Radiol

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“…1, 7) [25,26,35]. Scarce hepatic vessels with persistent enhancement are present within the infarcted portion of the liver [35]. This presentation is different from that of hepatic hematoma in which no internal enhancement is visible and the enhancing hepatic parenchyma is displaced and compressed [36].…”

Section: Hepatic Infarctionmentioning

confidence: 94%

“…Hepatic infarction is best depicted with MDCT that shows large, markedly hypoattenuating, peripheral area with persisting foci of enhancement that give a mottled appearance (Figs. 1, 7) [25,26,35]. Scarce hepatic vessels with persistent enhancement are present within the infarcted portion of the liver [35].…”

Section: Hepatic Infarctionmentioning

confidence: 97%

Hepatic involvement in HELLP syndrome: an update with emphasis on imaging features

et al. 2015

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HELLP syndrome, which consists of hemolysis, elevated liver enzymes, and low platelet count is an unusual complication of pregnancy that is observed in only 10% to 15% of women with preeclampsia. Hepatic involvement in HELLP syndrome may present with various imaging features depending on the specific condition that includes nonspecific abnormalities such as perihepatic free fluid, hepatic steatosis, liver enlargement, and periportal halo that may precede more severe conditions such as hepatic hematoma and hepatic rupture with hemoperitoneum. Maternal clinical symptoms may be nonspecific and easily mistaken for a variety of other conditions that should be recognized. Because hepatic hematoma occurring in association with preeclampsia and HELLP syndrome is a potentially life-threatening complication, prompt depiction is critical and may help reduce morbidity and mortality. This review provides an update on demographics, risk factors, pathophysiology, and clinical features of hepatic complications due to HELLP syndrome along with a special emphasis on the imaging features of these uncommon conditions.

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“…Hemorrhage can extend along the portal triads and form small pools of blood. In more severe cases, the hemorrhage can be more extensive, and it may dissect through the hepatic parenchyma into the subcapsular space and rupture through the capsule into the free intraperitoneal space (6,7). In severe cases, hemorrhage can be life-threatening.…”

Section: Toxemia Of Pregnancymentioning

confidence: 99%