Hepatic tumors: magnetic resonance and CT appearance.

Moss, Albert A.; Goldberg, Henry I.; Stark, DD; Davis, Peter L.; Margulis, A R; Kaufman, L; Crooks, L E

doi:10.1148/radiology.150.1.6316416

Cited by 104 publications

(29 citation statements)

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“…MR1 plays an important role in detecting and differentiating hepatic tumors [18,19]. A number of studies have suggested that FNH can be successfully differentiated from other liver tumors by virtue of isointensity on T1-WI and/or T2-W1, homogeneity, and a central scar which becomes hyperintense on T2-WI [3].…”

Section: Discussionmentioning

confidence: 99%

Focal nodular hyperplasia of the liver: Radiologic findings

et al. 1993

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A retrospective analysis of the results of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) of 24 cases (28 lesions) of proven focal nodular hyperplasia (FNH) is presented. While US exhibited nonspecific features, CT frequently showed characteristic features: hypodensity on precontrast scans (69%), transient immediate enhancement after bolus injection (96%), and homogeneity (85%). A scar was noted in 31% of the cases. The typical MR triad of isointensity on T1- and/or T2-weighted (T2-WI), homogeneity, and a scar which shows hyperintensity on T2-WI was seen in only 12% of our cases. The most common finding was homogeneity (94%). In two cases the scar was hypointense on T2-WI. To our knowledge, this finding has not been described before. We conclude that the features of FNH, although fairly constant, are at times indistinguishable from those of other hepatic tumors, such as hepatic adenoma (HA), fibrolamellar hepatocellular carcinoma (FLHCC), small hepatocellular carcinoma, and a hyperplastic nodule. Therefore, a multimodality approach is essential for the correct diagnosis in order to prevent unnecessary surgery.

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Section: Discussionmentioning

confidence: 99%

Focal nodular hyperplasia of the liver: Radiologic findings

et al. 1993

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“…In the mid-1980s, MRI had been reported as an efficient diagnostic tool for liver tumors [10], but only conventional spin-echo sequences with a lengthy acquisition time were available in the clinical setting. By the early 1990s, rapid acquisition sequences that allowed whole liver scanning during breath holding became available and gadolinium-enhanced dynamic MRI of the liver began to be used in daily radiologic practice [11].…”

Section: History Of Radiologic Diagnosis Of Hccmentioning

confidence: 99%

Magnetic Resonance Imaging of Hepatocellular Carcinoma

Kanematsu

Kondo²,

Goshima³

et al. 2008

Oncology

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In hepatocellular carcinomas (HCCs), T₁ shortening occurs due to internal protein, fat, copper, iron, hypercellularity, or a combination thereof. T₁-weighted magnetic resonance imaging (MRI) is obtained with a non-fat-suppressed phase shift [in- (4 ms) and opposed- (2 ms) phase] gradient-echo sequence. Internal fat deposition is often (36%) seen in well-differentiated HCCs between 1.1 and 1.5 cm in size. T₂-weighted MRI is crucial in differentiating HCCs from premalignant or borderline lesions in cirrhosis and serves as a tie breaker for small early-enhancing lesions. Gadolinium-enhanced MRI has advantages over contrast-enhanced CT: greater contrast enhancement, smaller volume of contrast, and less frequent adverse reactions. Double hepatic arterial-phase imaging has been performed in many centers, allowing less frequent off-timing arterial-phase imaging and improved temporary resolution. Hypervascular HCCs often show ‘corona’ enhancement in the late hepatic arterial phase, which makes it possible to distinguish small HCCs from enhancing pseudolesions. Liposoluble gadolinium chelate (e.g., Gd-EOB-DTPA) behaving both as an extracellular and hepatobiliary agent is very useful in the diagnosis. Diffusion-weighted imaging has become a routine imaging tool thanks to the parallel imaging technique. However, diffusion-weighted imaging may not significantly improve detection, characterization, or estimation of tumor grade for HCCs, and it should still be supplementary. In summary, we believe MRI outperforms CT in the diagnosis of HCCs.

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“…To our knowledge, few reports have been published about MR imaging of hepatic adenomas [3][4][5]. Moss et al [3] reported two cases of hepatic adenomas that were hyperintense on long TR/TE pulse sequences on a 0.…”

Section: Discussionmentioning

confidence: 99%

“…Moss et al [3] reported two cases of hepatic adenomas that were hyperintense on long TR/TE pulse sequences on a 0. …”

Section: Discussionmentioning

confidence: 99%

“…It is difficult to distinguish from well-differentiated hepatocellular carcinoma (HCC), both pathologically and radiologically [2]. MR imaging has become an important diagnostic technique for detecting and differentiating hepatic tumors [3,4]. The MR appearance of hepatic adenoma is variable, and MR has been unable to provide the specific diagnosis in reported cases [3][4][5].…”

Section: Mr Imaging Of Hepatic Adenomamentioning

confidence: 99%

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