Hepatitis A: A rare cause of acalculous cholecystitis in children

Acute Acalculous Cholecystitis due to Viral Hepatitis A

“…Indeed, by searching the MEDLINE database for published articles using the words “acalculous cholecystitis” and “viral hepatitis A,” we identified only 20 reports in the literature, including twenty-two patients with ACC due to acute viral hepatitis A [2, 3, 8–24] of which fifteen had appropriate information for analysis (Table 2). Four of these publications were in adults [9, 11, 13, 22]. …”

Acute acalculous cholecystitis due to hepatitis A infection in a child: A rare cause of acute abdomen

“…[1] This may be a more diagnostic finding for acute viral hepatitis than only gallbladder wall thickening which may occur in other clinical conditions such as cirrhosis, hypoalbuminemia, chronic renal failure, cardiac failure, or Kawasaki disease. [2,3] In conclusion, although gangrenous cholecystitis and perforation due to HAV infection are previously reported in childhood, generally the gallbladder abnormalities seen in the disease have a benign course and are self-limited. Generally, when perforation or other causes are excluded, acute cholecystitis due to HAV infection is treated satisfactorily by conservative treatment.…”

“…However in the literature, gangrenous cholecystitis, pleural effusions, and ascites due to HAV infection are rarely reported. [1][2][3][4] Although these complications of HAV infection are very rare, gallbladder abnormalities commonly occur during acute viral hepatitis infections. [5,6] These abnormalities include gallbladder wall thickening, gallbladder sludge, double-wall appearance.…”

“…Although HAV infection usually has a benign clinical course, it may exceptionally cause the fulminan hepatitis, pleural effusion, ascites, acute cholecystitis. [1][2][3][4] Acute acalculous cholecystitis due to HAV infection is very rarely reported in childhood. However, it may cause misdiagnosis and mistreatment when it occurs.…”

Acute acalculous cholecystitis revealing hepatitis A virus infection in children

“…The occurrence of acute acalculous cholecystitis (AAC) during HAV infection is uncommon and it has been exceptionally described in the literature. [12]…”