Hepatitis C virus and oral disease: a critical review

Roy, K.; Bagg, J.

doi:10.1111/j.1601-0825.1999.tb00089.x

Cited by 41 publications

(22 citation statements)

References 110 publications

(111 reference statements)

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“…Several reports have initially suggested an association between HCV and SS following the development of serological tests,[1415] which has been supported with more than 250 reported cases of SS–HCV. [35] Garcia-Carrasco et al .…”

Section: Sjogren's Syndrome and Salivary Gland Conditionsmentioning

confidence: 91%

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Oral conditions associated with Hepatitis C virus infection

Alavian

Mahboobi

et al. 2013

Saudi J Gastroenterol

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Hepatitis C virus (HCV) infection in more than 170 million chronically infected patients with no developed preventive vaccine is a globally important issue. In addition to expected hepatic manifestations, a number of extrahepatic manifestations, such as mixed cryoglobulinemia, glomerulonephritis, polyarteritis nodosa, rashes, renal disease, neuropathy, and lymphoma, have been reported following HCV infection, which are believed to be influenced by the virus or the host immune response. HCV combination therapy with pegylated interferon and ribavirin might be associated with side effects as well. The association of HCV with special oral conditions has also been reported recurrently; the mechanism of most of which remains unclear. This article reviews the association of HCV infection with some of the oral conditions such as oral health, Sjogren's syndrome, lichen planus and oral cancer.

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Section: Sjogren's Syndrome and Salivary Gland Conditionsmentioning

confidence: 91%

“…Therefore, the probable association between HCV infection and OLP could not be proved initially. [15]…”

Section: Lichen Planusmentioning

confidence: 99%

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Oral conditions associated with Hepatitis C virus infection

Alavian

Mahboobi

et al. 2013

Saudi J Gastroenterol

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“…There are six variants of OLP which include papular, reticular, plaque-like, atrophic, erosive, and bullous disease. Erosive mucosal disease is most problematic given the pain associated with the disease and can lead to oral candidiasis as well as carry premalignant risk [51,52]. Occasionally, the only identifying clue in OLP can be the sole presence of Wickham's striae.…”

Section: Lichen Planusmentioning

confidence: 98%

Cutaneous Manifestations of Viral Hepatitis

Ahmed

Said

2015

Curr Infect Dis Rep

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There are several extrahepatic cutaneous manifestations associated with hepatitis B and hepatitis C virus infection. Serum sickness and polyarteritis nodosa are predominantly associated with hepatitis B infection, whereas mixed cryoglobulinemia associated vasculitis and porphyria cutanea tarda are more frequently seen in hepatitis C infection. The clinico-pathogenic associations of these skin conditions are not completely defined but appear to involve activation of the host immune system including the complement system. Management of the aforementioned cutaneous manifestations of viral hepatitis is often similar to that done in cases without viral hepatitis, with control of immune activation being a key strategy. In cases associated with hepatitis B and C, control of viral replication with specific antiviral therapy is also important and associated with improvement in most of the associated clinical manifestations.

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“…In different studies, diseases such as ulcerative colitis, alopecia, areata, vitiligo, dermatomyositis, morphia, thymoma, myasthenia gravis, hypogammaglobulinemia and primary biliary cirrhosis are reported to occurredin lichen planus patients (Burns T 2004;Greenberg MS 2008). Some studies showed association of lichen planus with HIV and HCV (Gandolfo et al 1994;Roy and Bagg 1999;Klanrit et al 2003;Pilli et al 2002;Emadi et al 2010). Recent studies revealed that specific T lymphocytes related to chronic HCV infectionhave been defined in oral mucosa of chronic HCV and OLP patients (Pilli et al 2002).…”

Section: Association With Other Diseasesmentioning

confidence: 99%