Hepatitis D virus infection in Slovenian patients with chronic hepatitis B virus infection: a national prevalence study and literature review

Jelen, Mateja M.; Hošnjak, Lea; Stunf, S; Zagožen, Anja; Komloš, Kristina Fujs; Markocic, P.; Poljak, Mario; Seme, Katja

doi:10.15570/actaapa.2016.14

Cited by 5 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It appears from this work that the prevalence of anti-HDV antibodies was 3.9% Open Journal of Gastroenterology in patients followed for hepatitis B in Cotonou. This prevalence is higher than the 0.23% found in 2015 in Slovenia [14]. It is comparable to the prevalence of 3.5% reported in 2011 in France [5].…”

Section: Discussionsupporting

confidence: 56%

Hepatitis D in Patients Infected with Hepatitis B Virus in Cotonou: Characteristics and Risk Factors

Kpossou¹,

Sogbo²,

Zomahoun³

et al. 2020

OJGas

View full text Add to dashboard Cite

Introduction: Hepatitis D virus (HDV) is a satellite virus of hepatitis B virus (HBV). The purpose of this work was to describe the epidemiological, clinical and biological characteristics of HBV/HDV co-infection and the factors associated with this co-infection in Cotonou. Methods: This was a cross-sectional, descriptive study with prospective data collection. It took place from June to October 2016 at CNHU/HKM and the Atinkanmey Polyclinic in Cotonou. Subjects over 15 years of age with HBsAg and untreated for hepatitis were included consecutively. Sociodemographic, clinical and biological characteristics were collected for each patient using only a standardized questionnaire. Then, a blood sample was taken for the determination of anti-HDV antibodies as well as the viral load of HBV. Results: A total of 156 subjects were included, predominantly male (sex-ratio = 2), and of median age 36 years. The majority were monogamous married (50%) or single (41.7%), and were from south of Benin (84.6%). Most subjects were asymptomatic (49.4%). The prevalence of total HDV antibodies was 3.9% (6/156). In subjects with total HDV antibodies, the prevalence of HDV IgM was 33.3%. Origin in northern Benin appears to be a risk factor for HDV infection (p = 0.042). Similarly, married subjects were statistically more infected with HDV than unmarried subjects (p = 0.002). Conclusion: The prevalence of HDV infection varies according to the origin of the patients and their marital status.

show abstract

Section: Discussionsupporting

confidence: 56%

Hepatitis D in Patients Infected with Hepatitis B Virus in Cotonou: Characteristics and Risk Factors

Kpossou¹,

Sogbo²,

Zomahoun³

et al. 2020

OJGas

View full text Add to dashboard Cite

show abstract

“…Here, 6.5% of HBsAg positive patients in Israel were found to be HDV seropositive, a higher rate than the estimated 5% worldwide prevalence [30]. Reported HDV prevalence varies in different European countries between very low (0.23%) in Slovenia to high (35.3%) prevalence in Greece [31]. In Lebanon HDV prevalence reported in 258 HBV positive individuals was only 1.2% [32].…”

Section: Discussionmentioning

confidence: 99%

Characterization of hepatitis B and delta coinfection in Israel

et al. 2018

View full text Add to dashboard Cite

The overall significant prevalence of HDV (6.5%) mandates HDV RNA testing for all coinfected patients. Patients positive for HDV RNA (characterized by low HBV DNA blood levels) carried HDV genotype 1. Taken together, the significant HDV seroprevalence and the lack of effective anti-HDV therapy, necessitates strict clinical surveillance especially in patients with higher HDV viral loads and increased viral evolution.

show abstract

“…In Europe, the prevalence of HDV among HBsAg-positive people was estimated at 3.0% for general population and 19.5% for patients in hepatology clinics [ 16 ]. Thanks to vaccination against HBV, compulsory testing of blood products and improvements in socio-sanitary conditions, HDV prevalence has decreased in most European countries over the last 20 years [ 12 ]. Overall, around 445,000 people in Europe are considered infected with chronic HDV [ 27 ].…”

Section: The Contemporary Patterns Of Chronic Hepatitis D: a Literatu...mentioning

confidence: 99%

“…In Europe, HDV infection is maintained by two different remaining pockets of HDV-infected individuals: young people who immigrate from less-developed areas where HDV is endemic, and a domestic pool of older individuals who represent the tail of an infection acquired decades ago during the HDV endemic period [ 12 ].…”

Section: The Contemporary Patterns Of Chronic Hepatitis D: a Literatu...mentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology Pattern, Prevalent Genotype Distribution, Fighting Stigma and Control Options for Hepatitis D in Bulgaria and Other European Countries

Tsaneva

Georgieva

2023

Life

View full text Add to dashboard Cite

Hepatitis D virus (HDV) is a satellite virus that causes the most aggressive form of all viral hepatitis in individuals already infected with HBV (hepatitis B virus). In recent years, there has been a negative trend towards an increase in the prevalence of chronic hepatitis D in Europe, especially among immigrant populations coming from regions endemic for the virus. The aim of this review is to analyse the current epidemiology of chronic HDV, routes of transmission, prevalent genotype, its management, prevention, fighting stigma and options for viral control in European countries, such as Bulgaria.

show abstract

Hepatitis D virus infection in Slovenian patients with chronic hepatitis B virus infection: a national prevalence study and literature review

Abstract: This study included 1,305 HBsAg-positive serum samples obtained from the same number of patients randomly selected from all 2,337 patients with chronic hepatitis B referred to the Slovenian national reference laboratory for viral hepatitis at the

Cited by 5 publications

References 31 publications

Hepatitis D in Patients Infected with Hepatitis B Virus in Cotonou: Characteristics and Risk Factors

Hepatitis D in Patients Infected with Hepatitis B Virus in Cotonou: Characteristics and Risk Factors

Characterization of hepatitis B and delta coinfection in Israel

Epidemiology Pattern, Prevalent Genotype Distribution, Fighting Stigma and Control Options for Hepatitis D in Bulgaria and Other European Countries

Contact Info

Product

Resources

About