1996
DOI: 10.1111/j.1600-0684.1996.tb00205.x
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Hepatocellular carcinoma in a squirrel monkey (Saimiri sciureus)

Abstract: A well-differentiated hepatocellular carcinoma of the liver was diagnosed in a female squirrel monkey. The lesion showed trabecular, solid and glandular features that are characteristics of malignant liver tumours.

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Cited by 12 publications
(10 citation statements)
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“…In the chimpanzee, several of the known cases have been secondary to experimental infection with hepatitis B and hepatitis C virus (Porter et al, 2004a). Hepatocellular carcinomas have also been observed in two species of squirrel monkey, S. boliviensis (Borda et al, 1996) and S. sciureus (Morris and Abdi, 1996), cynomolgus macaques (Reindel et al, 2000), an African green monkey (Seibold and Wolf, 1973), and experimentally in rhesus macaques exposed to a variety of carcinogens including nitrosomines and aflatoxin (Adamson, 1989). A hepatoma has been recorded in a sooty mangabey (Clark and Olsen, 1973) and a hepatic neuroendocrine tumor has been reported in a baboon (Aloisio et al, 2009).…”
Section: Tumors Of the Digestive Systemmentioning
confidence: 96%
“…In the chimpanzee, several of the known cases have been secondary to experimental infection with hepatitis B and hepatitis C virus (Porter et al, 2004a). Hepatocellular carcinomas have also been observed in two species of squirrel monkey, S. boliviensis (Borda et al, 1996) and S. sciureus (Morris and Abdi, 1996), cynomolgus macaques (Reindel et al, 2000), an African green monkey (Seibold and Wolf, 1973), and experimentally in rhesus macaques exposed to a variety of carcinogens including nitrosomines and aflatoxin (Adamson, 1989). A hepatoma has been recorded in a sooty mangabey (Clark and Olsen, 1973) and a hepatic neuroendocrine tumor has been reported in a baboon (Aloisio et al, 2009).…”
Section: Tumors Of the Digestive Systemmentioning
confidence: 96%
“…A large number of squirrel monkeys are kept in zoos and experimental facilities, but there are few reports of tumors in this species such as malignant lymphoma [1], hepatocellular carcinoma [3,11], osteosarcoma [8], adenocarcinoma of the cecum [9], squamous cell carcinoma of the oral cavity [12], and mammary adenocarcinoma [14]. In the present study, we describe a case of subcutaneous leiomyosarcoma in the right axilla with pulmonary metastasis in a squirrel monkey.…”
mentioning
confidence: 99%
“…Hepatocellular carcinoma (HCC) has been reported in seven of approximately 300 extant NHP species . The etiology in most of these cases was undetermined.…”
Section: Discussionmentioning
confidence: 99%
“…Experimentally induced or naturally occurring HCC has been reported in chimpanzees ( Pan troglodytes ); common squirrel monkey ( Saimiri sciureus ) and black‐capped squirrel monkey ( Saimiri boliviensis ); cynomolgous ( Macaca fascicularis ), rhesus ( Macaca mulata ), and Japanese macaques ( Macaca fuscata ); African green monkey ( Cercopithecus aethiops ); and golden‐headed lion tamarins ( Leontopithecus chrysomelas ) . Other PLNs reported in NHPs are hepatoma in sooty mangabey ( Cercocebus atys ); neuroendocrine carcinoma in baboon ( Papio sp.…”
Section: Introductionmentioning
confidence: 99%