Background
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and it often develops in patients with underlying liver cirrhosis. The prevalence of HCC in cirrhotic patients is a significant concern, as it poses a high risk of morbidity and mortality. Aim of this study was Evaluating Hepatocellular carcinoma Prevalence in cirrhotic patients and influencing factors among patients admitted to Urmia Imam Khomeini Hospital ; North-West of Iran from 2016 to 2020.
Methods
This is a cross-sectional study. Data on hepatocellular carcinoma prevalence and cirrhotic influencing factors were collected from medical records of patients admitted to Imam Khomeini Hospital from 2016 to 2020.
Results
During the four-year study period, a total of 427 number of patients were admitted to Imam Khomeini Hospital with cirrhotic conditions. Mean (SD) of patients were 59.73(15.3) years. The diagnose rate of HCC was 10.77% (95% CI = 8–14%). HBV and HCV positivity were 26.1% (95% CI = 22–30%) and 6.1% (95% CI = 4–88%) among studied population respectively. HBV and HCV positivity were 63.04% (95% CI = 47–77%) and 10.86% (95% CI = 3.6–26%) among HCC respectively. Rate of reported alcohol consumption was 9.84% (95% CI: 7.18–13.06%). In cirrhotic patients, HBV and Cryptogenic cirrhosis were the most underlying disease among cirrhotic patients (26% and 18.7% of cases, respectively). HBV, Cryptogenic cirrhosis and alcoholic cirrhosis were the most underlying disease among in HCC patients (63% and 4.35% and 4.35% of cases, respectively).
Conclusions
The research highlights that liver cancer and hepatocellular carcinoma are not the most common cancers in this province, however due to the increasing trend of its predisposing factors and underlying diseases, It is important to have screening programs for people at high risk.
