2016
DOI: 10.1016/j.biopha.2016.06.023
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Hepatoprotective and antioxidant potential of Asphodeline lutea (L.) Rchb. roots extract in experimental models in vitro/in vivo

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Cited by 10 publications
(3 citation statements)
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“…The hepatic injury was evaluated by measuring liver markers (AST, ALT, ALP, GGT, TB) [36] (Table 2). ACLF induction by D-Gal-LPS caused a severe increase of the liver markers than in Control animals (p < 0.001).…”
Section: Biochemical Serum Analysismentioning
confidence: 99%
“…The hepatic injury was evaluated by measuring liver markers (AST, ALT, ALP, GGT, TB) [36] (Table 2). ACLF induction by D-Gal-LPS caused a severe increase of the liver markers than in Control animals (p < 0.001).…”
Section: Biochemical Serum Analysismentioning
confidence: 99%
“…The chemotherapeutic value of Bulgarian and Turkish AL root extracts has been evidenced only in recent years, revealing the presence of different therapeutically useful compounds. The anti-microbial and anti-mutagenic activities of methanol root extracts of AL have been reported [ 5 ], while the hepatoprotective and antioxidant capacity of the ethanol root extracts of AL both in vivo and in vitro has also been evidenced in an animal model of CCl 4 -injured liver [ 6 ]. Moreover, the methanol and chloroform extracts from AL roots caused a marked inhibition of multidrug resistance in mouse tumour cells transfected with the human MDR1 gene [ 7 ], whereas methanol, acetone and aqueous extracts of different Asphodeline spp.…”
Section: Introductionmentioning
confidence: 99%
“…Başta antrokinonlar, fenolik asitler ve flavonoidler olmak üzere çeşitli bileşikler bu çalışmalarda rapor edilmiştir [11,[18][19][20][21][22][23][24]. Yine yapılan çeşitli çalışmalarda Asphodeline üyelerinin antioksidan, antimikrobiyal, antikanser ve karaciğer koruyucu özellikler gibi biyolojik aktiviteleri de belirlenmiştir [11,[19][20][21][22][23][24][25][26][27][28]. Bununla birlikte cins üyelerinin kimyasal profilleri ve biyolojik aktiviteleri üzerine yapılan çalışmalar halen yeterli seviyede değildir.…”
Section: Introductionunclassified