Herbal Drug Standardization: A Systemic Review

Lamichhane, Suman; Sahariah, Bhargab Jyoti; Das, Bhaswati; Khatiwara, Deepika; Sola, Piyong; Adhikari, Rudra Prasad; Gogoi, Bitu; Alam, Tahid

doi:10.22270/jddt.v13i4.6012

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…In the field of micros, several variables are considered. 52,53 • Content of leaves • Trichome, • Stomata…”

Section: • Microscopicmentioning

confidence: 99%

Elevating Herbal Therapies: A Deep Dive into Standardization

FA,

DT,

2024

IJPQA

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Around 80% of the global population incorporates medicinal products made from herbs. Herbs play a major role in conventional medicine and are also frequently employed in naturopathic, homeopathic, ayurveda, and other healthcare practices. The herbal products are vulnerable to intrusion from numerous paths, degradation, and changes in their chemical structure because they are predominantly organic (plant-based). Hence, it is crucial to establish and implement quality control criteria for medicinal products made from herbs to guarantee both their safety and effectiveness. There are numerous factors in standardization alone, including gross morphology, microscopy, physical characteristics, and chemical, chromatographic, and spectroscopic fingerprinting. Standardization of herbal medications increases their security and therapeutic efficacy while potentially gaining global popularity. Because herbal remedies are derived from natural sources, adverse reactions, counterfeiting, and tampering are less likely. From this review, the concept of standardization of herbal drugs, as well as their classification, advantages, and limitations, is described. It also includes the need and scope for standardization of herbal drugs, its standardization method, and pharmacopeial standards.

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“…In the field of micros, several variables are considered. 52,53 • Content of leaves • Trichome, • Stomata…”

Section: • Microscopicmentioning

confidence: 99%

Elevating Herbal Therapies: A Deep Dive into Standardization

FA,

DT,

2024

IJPQA

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“…Extraction methods can also affect the concentration of the active compounds, and contamination with other substances can occur during the production process. Additionally, natural products may interact with other medications or exhibit unpredictable effects due to individual genetic differences [28]. To address these challenges, various standardization methods have been proposed, including the use of reference compounds, phytochemical profiling, and bioassays.…”

Section: Challenges Associated With the Development Of Natural Produc...mentioning

confidence: 99%

From Traditional Medicine to Modern Drug Development: Natural Products Targeting Amyloid Plaque in Alzheimer's Disease

2023

BSCR

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Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people worldwide, and its pathogenesis is characterized by the formation of amyloid plaque in the brain. Current treatments for AD are limited and only offer symptomatic relief, making the development of new therapies a crucial area of research. One promising approach is the use of natural products, which have been used in traditional medicine for centuries and are a rich source of bioactive compounds. In this review, we discuss the use of natural products for the treatment of AD, with a particular focus on those that target amyloid plaque formation and clearance. We highlight the mechanisms of action of these natural products, including inhibition of amyloid-beta (Aβ) aggregation, promotion of Aβ degradation, and modulation of Aβ-induced neuroinflammation. We also discuss the challenges associated with the development of natural products as therapeutics, including issues related to standardization, quality control, and safety. Finally, we examine the potential of combining natural products with modern drug development approaches, such as nanotechnology and synthetic biology, to overcome these challenges and develop effective treatments for AD.

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