Herbal infusions and health

Etheridge, Christopher J.; Derbyshire, Emma

doi:10.1108/nfs-08-2019-0263

Cited by 27 publications

(14 citation statements)

References 48 publications

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“…Although this experimental design is weaker than a randomized controlled trial with respect to establishing a cause-effect relationship, before-and-after approaches have been widely used. [50][51][52][53][54] Moreover, the present single-group beforeafter design could be biased by the modification of the subjects' lifestyle (Hawthorne effect). According to previous studies protocols, [55][56][57][58][59] participants were instructed not to modify their dietary and physical habits.…”

Section: Discussionmentioning

confidence: 99%

Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Cruz‐Chamorro

Álvarez-Sánchez

Álvarez-Ríos

et al. 2021

Molecular Nutrition Food Res

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Scope: We have previously demonstrated the anti-inflammatory and antioxidant properties of in vitro administered Lupinus angustifolius protein hydrolysates (LPHs) on human peripheral blood mononuclear cells (PBMCs). This study aims to evaluate the safety and efficacy of a beverage containing LPHs (LPHb) on the immune, oxidative and metabolic status of healthy subjects. Methods and Results: In this open-label intervention, 33 participants daily ingest a LPHb containing 1 g LPHs for 28 days. Biochemical parameters are assayed in fasting peripheral blood and urine samples before, during (14 days) and after LPHb ingestion. Participants' health status and the immune and antioxidant responses of PBMCs are also evaluated throughout the trial. The LPHb ingestion is safe and effective in both increasing the anti-/proinflammatory response of PBMCs and improving the cellular anti-oxidant capacity. LPHb also reduces the low-density lipoprotein-cholesterol (LDL-C)/high-density lipoprotein-cholesterol (HDL-C) atherogenic index. LPHb effect is particularly beneficial on decreasing not only the LDL-C/HDL-C index but also serum total cholesterol levels in the male cohort that shows the highest baseline levels of well-known cardiovascular risk factors. Conclusion: This is the first study to show the pleiotropic actions of a lupine bioactive peptides-based functional food on key steps of atherosclerosis including inflammation, oxidative stress, and cholesterol metabolism.

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Section: Discussionmentioning

confidence: 99%

Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Cruz‐Chamorro

Álvarez-Sánchez

Álvarez-Ríos

et al. 2021

Molecular Nutrition Food Res

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“…There are around 3 billion people who enjoy drinking tea and infusions globally with this seen as an inexpensive complementary alternative medicine [27]. It has been previously reported that tea and herbal infusions are a valuable source of flavonoids and other polyphenols and that ingestion (around 1 to 3 cups daily) could potentially benefit certain aspects of health [28]. In particular, L-theanine, an amino acid naturally found in green and black tea (Camellia sinensis) is thought to help attenuate the negative effects of psychological stress and anxiety on health [29].…”

Section: Resultsmentioning

confidence: 99%

Tea and Herbal Infusions, Psychological Stress, Anxiety & Sleep Health: A Systematic Review of Human Trials & Mechanistic Studies

Derbyshire¹,

Bond²,

Ellis³

2023

Nutr Food Technol Open Access

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Tea is popular global beverage and abundant provider of biologically active plant molecules which have been attributed to its health properties. Relationships between tea drinking and certain aspects of health have been the subject of past reviews. The present systematic review focuses on tea consumption in relation to psychological stress and the challenges of stress and anxiety on sleep health. Publications were searched up to 21st September 2022, in the PubMed database along with references of original articles. Thirty-three publications were included in the main review-17 human trials and 16 mechanistic studies. Human trials were graded to assess quality using the Jadad scale. Overall, a growing body of evidence suggests that tea (including green and oolong) and herbal infusions, at relatively low intakes (around 1 to 2 cups daily), could help to facilitate sleep, alleviate psychological stress and anxiety, primarily by facilitating relaxation. Evidence for black tea, German Chamomile, Lavender, Rose, Jasmine, and Passionflower tea is emerging and looks promising. Ongoing research is needed in the form of randomised controlled trials to build on these provisional findings.

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“…Mixture of herbal infusions have high anti-oxidant activities that could play a role in the management of health conditions such as diabetes (Etheridge and Derbyshire, 2019). WUB was tested by liquid chromatography-mass spectrometry (LC-MS) to identify phenolic compounds qualitatively with positive ionization mode.…”

Section: Resultsmentioning

confidence: 99%

Traditional drink of blackcincau(Mesona palustrisBL)-basedwedang uwuhas immunomodulator on alloxan-induced diabetic rats

Widyaningsih

Siska

Fanani

et al. 2020

NFS

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Purpose This study aims to evaluate the immunomodulatory effect of traditional drink of black cincau-based wedang uwuh (WUB) on alloxan-induced diabetic rats. Design/methodology/approach WUB consists of dried herbs such as black cincau leaves (Mesona palustris BL), red ginger (Zingiber officinale Rosc), cloves (Syzgium aromaticum), sappan wood (Caesalpinia sappan Lin) and soursop leaves (Annona muricata). In this study, the rats were divided into five groups: normal control, diabetic control and three groups of WUB (WUB 13.5 mL/kg and WUB 27 mL/kg) or wedang uwuh commercial (WUC) treated diabetic groups. WUB or WUC was administered by gavage for three days after rats were confirmed diabetic induced by alloxan; these injections were continued for 28 days. At the end of the experiment, the spleen of rats was analyzed using flow cytometry. Data were analyzed by ANOVA followed by Tukey test using Minitab version 16.0. Findings This study showed that WUB significantly inhibited the expression of pro-inflammatory cytokines (interferon-Y [IFN-ɣ] and tumor necrosis factor-α [TNF-a]) and anti-inflammatory cytokines (interleukin 10 [IL-10] and transforming growth factor-β [TGF-ß]), and achieved a balance between pro-inflammatory and anti-inflammatory cytokines that were not significantly different from normal controls. WUB 27 was able to regulate the production of relative average cytokines IFN-ɣ (7.6 ± 3.5; p = 0.010), TNF-a (8.7 ± 2.4; p = 0.018), IL-10 (6.3 ± 2.4; p = 0.001) and TGF-ß (7.4 ± 2.1; p = 0.004) that was significantly different from diabetic control. This study’s results validate that the use of WUB can result in immunomodulatory activity in diabetic rats. Originality/value To the best of the authors’ knowledge, this is the first study on the immunomodulatory effect of WUB which is developed based on WUC; WUB has been used by Indonesian people as a functional beverage which acts as an immune booster and body warmer.

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Herbal infusions and health

Cited by 27 publications

References 48 publications

Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Tea and Herbal Infusions, Psychological Stress, Anxiety & Sleep Health: A Systematic Review of Human Trials & Mechanistic Studies

Traditional drink of blackcincau(Mesona palustrisBL)-basedwedang uwuhas immunomodulator on alloxan-induced diabetic rats

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