Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis

Hong, Seungcheol; Park, Bongki; Noh, Hyeon-seok; Choi, Do Lim

doi:10.1177/1534735419873404

Cited by 5 publications

(3 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, the advent of new regimens [3][4][5] and surgical treatments [8][9][10][11] and specific side effects related to these (such as skin rashes, peripheral neuropathy, mucositis), may not be present in the existing HRQoL measures.…”

Section: Discussionmentioning

confidence: 99%

“…Contemporary operative treatments using less-invasive approaches have also been introduced, including laparoscopic and robotic surgery. These systemic treatments and surgical advances may have more favourable outcomes in terms of treatment-related toxicities; however, they have unusual side effects previously not seen, including skin rashes, mucositis, and peripheral neuropathy [6,7] while surgical-related side effects include 'dumping syndrome', reactive hypoglycaemia and chronic nutritional problems [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences

et al. 2022

View full text Add to dashboard Cite

The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL) which need careful monitoring. While there are HRQoL measures designed specifically to capture issues relevant to patients with GC, these might be outdated and only relevant to patients in westernised cultures. This review identifies the patient-reported measures used to assess HRQoL of patients with GC and compares the HRQoL measures used across cultures including East Asia, where GC is more prevalent. We conducted a systematic review of publications between January 2001 and January 2021. A total of 267 papers were identified; the majority (66%) of studies involved patients from East Asian countries. Out of the 24 HRQoL questionnaires captured, the European Organisation for Research and Treatment of Cancer Core Cancer measure (QLQ-C30) was the most widely used (60% of all studies and 62% of those involving patients from East Asian countries), followed by its gastric cancer-specific module (QLQ-STO22, 34% of all studies and 41% from East Asia). Eight questionnaires were developed within East Asian countries and, of the 20 studies including bespoke questions, 16 were from East Asia. There were six qualitative studies. HRQoL issues captured include diarrhoea, constipation, reflux, abdominal pain and abdominal fulness or bloating, difficulty swallowing, restricted eating, and weight loss. Psychosocial issues related to these problems were also assessed. Issues relating to the compatibility of some of the westernised measures within East Asian cultures were highlighted.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In this context, the exploration of alternative treatments, particularly HM, emerges as a promising solution. Prior studies indicate that herbal treatments have the potential to significantly enhance GI function, nutritional status, and immune function, while potentially mitigating complications associated with gastric cancer surgery [29,30]. This study was undertaken to systematically investigate the efficacy of HM in addressing these challenges and assess its impact on the recovery of patients with early GC.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of Herbal Medicine Treatment on Post-Surgical Recovery in Gastric Cancer Patients: A Systematic Review and Meta-Analysis

Kim,

Pyo,

Kim

et al. 2024

Preprint

View full text Add to dashboard Cite

Background: Gastric cancer (GC) is the second most prevalent cancer in Korea, significantly impacting morbidity and mortality. While advancements in early detection and treatment have improved survival rates, managing post-surgical recovery remains vital. Herbal medicine (HM) has emerged as a potential adjunct therapy to enhance recovery and quality of life (QoL) in patients post-GC surgery. Methods: This systematic review and meta-analysis evaluated the efficacy and safety of HM in the post-surgical recovery of GC patients. We searched both Korean and international databases, identifying 16 randomized controlled trials (RCTs) meeting our criteria. We assessed study quality using the Cochrane Risk of Bias tool and analyzed data with Review Manager Software (RevMan). Results: Our analysis included 1,546 patients from the selected studies, demonstrating that HM significantly improved gastrointestinal recovery times, including time to first flatus, bowel movement, and return of bowel sounds. Significant improvements were also seen in nutritional markers such as albumin and prealbumin, alongside beneficial effects on immune markers like CD3+ and CD4+ levels. QoL assessments using WHOQOL-BREF and QLQ-C30 scores indicated substantial improvements. HM had a favorable safety profile, showing a reduced incidence of adverse effects compared to controls. Conclusion: The findings suggest that HM can significantly enhance recovery and improve the quality of life following gastric cancer surgery, with a favorable safety profile. However, due to considerable heterogeneity in study results, extended clinical trials and rigorous follow-ups are recommended to assess long-term effects and side effects comprehensively.

show abstract