Herpes zoster during the COVID-19 pandemic

Abstract

Varicella-zoster virus leads to primary infection, i.e. varicella, and remains in latent form in sensory dorsal root ganglion cells. Further replication and manifestation of skin lesions characteristic for herpes zoster may occur many years later. Primary cutaneous eruptions are blisters, filled with serous content, grouped on an erythematous area, merging into larger blisters. The virus reactivates most often in elderly people, people with impaired immunity, as well as those undergoing radiotherapy or excessive exposure to UV radiation. Recently, many studies indicate a relationship between SARS-CoV-2 and reactivation of varicellazoster virus. It is suggested that skin lesions characteristic for herpes zoster can be the first sign of COVID-19, can coexist with SARS-CoV-2 infection or can appear after recovery.

Activation of Herpes Viral Infection as a Manifestation of Post-Covid Syndrome

“…Авторы предполагают, что клиническую картину герпеса в период пандемии SARS-CoV-2 даже у пациентов с легкими или предположительными симптомами со стороны верхних дыхательных путей в анамнезе следует рассматривать как признак недавней субклинической инфекции SARS-CoV-2. Польские авторы указывают на связь активации герпес-вирусной инфекции с COVID-19 [37], причем активация герпеса у пациента может позволить заподозрить у него наличие инфекции SARS-CoV-2.…”