Heterostructured bismuth oxide/hexagonal-boron nitride nanocomposite: A disposable electrochemical sensor for detection of flutamide

2D Boron Nitride Heterostructures: Recent Advances and Future Challenges

“…An h‐BN/Bi 2 O 3 composite with the formation of Bi‐O‐B bonding at the interfaces has been synthesized by solvothermal treatment at 165 °C for 4 h. The system works well as a sensor of flutamide, a nonsteroidal anti‐androgen drug for the treatment of prostate cancer. [ 56 ] The mixed bonding modifies the Bi 2 O 3 bandgap because of the electron transfer at the interface, which increases to 5.7 eV for the h‐BN/Bi 2 O 3 composite. The difference in the work function between h‐BN and Bi 2 O 3 , 5.81 and 4.7 eV, respectively, causes an upward Bi 2 O 3 band bending and an electron transfer process while forming the heterojunction ( Figure ).…”

Recent advances in 2D hexagonal boron nitride (2D-hBN) applied as the basis of electrochemical sensing platforms

“…In a similar vein, β-agonists have been shown to be electroanalytically detected in urine samples using 2D-hBN/multi-walled carbon nanotube nanocomposite modified GCE in the presence of ascorbic acid and uric acid [64]. Other approaches have combined 2D-hBN with graphene for the detection of nicotine applied in real tobacco samples [65] and 2D-hBN with bismuth oxide for the sensing of flutamine applied in environmental samples [66]. In all cases, the synergy of mixing the various components comprising the nanocomposite is attributed to the beneficial electrochemical response.…”

A low-cost and facile electrochemical sensor for the trace-level recognition of flutamide in biofluids using large-area bimetallic NiCo2O4 micro flowers

“…Flutamide is a non-steroidal anti-testosterone drug extensively used for treating prostate cancer. 1 It does not cure prostate cancer but it can effectively control the growth and spread by blocking the interaction of dihydrotestosterone and testosterone with the prostate tissues. 2,3 Besides, this drug is used for hormonal treatments such as polycystic ovary syndrome.…”

“…Kokulnathan et al reported the screen-printed carbon electrode adapted with the bismuth oxide/hexagonal-boron nitride nanocomposite heterostructure for flutamide detection. 1 Brahman et al reported a ferrocene and multi-walled carbon nanotubefunctionalized carbon paste electrode for the detection of flutamide in biofluids using the square wave voltammetry (SWV) technique. 2 Karthik et al reported an electrochemical sensor for flutamide detection in blood serum samples using graphene oxide via the linear sweep voltammetry (LSV) technique.…”

“…TMOs have attracted significant interest in the development of electrochemical biosensors due to their unique structure, high biocompatibility, multiple oxidation states, and high chemical stability. 1 Generally, bimetallic compounds exhibit enhanced electrocatalytic properties over their monometallic oxide counterparts, which can be ascribed to synergetic effects. 8,9 Peng et al reported that the mixed valence state of bimetallic compounds was responsible for the enhanced electrocatalytic activity, which proves it as a unique and capable platform for the electrochemical sensing of small biomolecules in biofluids.…”