Hexadecyl gellan amphiphilic nanoparticles: Physicochemical properties and in vivo lipid-lowering potential

Kundu, Payel; Datta, Rana; Maiti, Sabyasachi

doi:10.1016/j.jddst.2015.03.004

Cited by 7 publications

(1 citation statement)

References 34 publications

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“…The nanosuspension showed negative zeta potentials (-27.4 to -28.2 mV), which indicates a high stability over time. The system increased the bioavailability of the encapsulated drug, increasing its water solubility up to 355 times [43]. The same group of authors obtained a micellar system based on cetyl-GG, with particle sizes around 832 nm, which caused a considerable rise in solubility of simvastatin in water.…”

Section: Micellesmentioning

confidence: 96%

Drug Delivery Systems Based on Gellan Derivatives

BAROI,

POPA,

HAMCERENCU

et al. 2024

AnnalsARSciPhysChem

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This paper proposes a review of the literature that reports valuable and interesting results regarding the biomedical applications of gellan and its derivatives. The different types of formulations for which this microbial exopolysaccharide is suitable are listed, which depend on the condition to be treated and their administration method: tablets, films, gels synthesized in situ, hydrogels, different types of particles, especially micro- and nanoparticles , mice etc. Research on the biomedical uses of gellan and its derivatives is far from being exhausted, newer directions regarding the creation of nanocomposites (with clays, for example), of mixtures or semi- and interpenetrated networks with other polymers revealing the obtaining of new extremely valuable biomaterials not only as supports for the encapsulation, transport and release of drugs, but also in the field of tissue engineering.

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Section: Micellesmentioning

confidence: 96%