Hidden dangers among circuit parties—A systematic review of HIV prevalence, sexual behaviors and drug abuse during the biggest gay events

Troiano, Gianmarco; Mercurio, Isabella; Bacci, Mauro; Nante, Nicola

doi:10.1080/10911359.2018.1479671

Cited by 10 publications

(9 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the STI, Neisseria gonorrhoeae infections are a significant public health problem and represent the second most common reportable diseases in the United States [19]. Most cases of gonorrhoea are identified in the urogenital tract but, among men who report sex with men (MSM), it is also common the pharyngeal gonorrhoea with a prevalence ranging from 2-11% [20,21]. Previous reviews highlighted that gonorrhoea disproportionately affects marginalized populations.…”

Section: Discussionmentioning

confidence: 99%

Impact of MenB Vaccination on Neisseria gonorrhoeae infections: a comprehensive state-of-the-art review

Troiano¹,

Nardi²

2022

Ital J Gynaecol Obstet

View full text Add to dashboard Cite

Objective. N. gonorrhoeae is a human-restricted pathogen but, nowadays, no effective anti-gonococcal vaccine is available. Several studies showed that OMV-based MenB vaccines may provide a cross-protection against gonococcal infections, so the aim of our study was to investigate, through a review of the literature, the state of art about the potential impact of meningococcal B vaccination on gonococcal infections. Materials and Methods. In February 2021 we performed a search for original peer-reviewed papers in the electronic database PubMed (MEDLINE). The key search terms were "Meningitis B AND Gonorrhoea", "Bexsero AND Gonorrhoea", "MenB vaccine AND Gonorrhoea", "Trumenba AND Gonorrhoea". Studies that provided clear and sufficient data on the impact of MenB vaccination on gonorrhoea were included.Results. Bibliographic research yielded 39 publications, but the overall analysis was conducted on 5 studies. Despite the limited number of included studies, and their heterogeneity it was observed a reduced incidence of N. gonorrhoeae infections and the elicitation of antibody response. Conclusions. Although MEN B vaccination could be taken in consideration as an interesting strategy to prevent N. gonorrhoeae infection, further studies are fundamental to establish a real and durable vaccine effectiveness.

show abstract

Section: Discussionmentioning

confidence: 99%

Impact of MenB Vaccination on Neisseria gonorrhoeae infections: a comprehensive state-of-the-art review

Troiano¹,

Nardi²

2022

Ital J Gynaecol Obstet

View full text Add to dashboard Cite

show abstract

“…A large body of evidence confirms the wide-ranging negative impacts of non-adherence [40,[43][44][45][46][47][48]. Other studies have demonstrated that RD use is associated with poor social, mental and financial health [33,34,38,40,42]. CM are also known as 'traditional' or 'alternative' medicines and include substances such as vitamins, minerals, herbal remedies, aromatic oils and homeopathic products [49].…”

Section: Introductionmentioning

confidence: 99%

“…For people who take ART, either as prevention or as treatment, the potential for RD to interact with ART causing harm is of major concern [28,[32][33][34][35][36][37]. For example, Bracchi and colleagues [32] describe how RD such as benzodiazepines, ketamine, crystal methamphetamine, methylenedioxymethamphetamine and mephedrone can modulate the metabolism of commonly prescribed ART and decrease the concentration of some to subtherapeutic levels (with the consequent risk of treatment resistance), while causing the accumulation of others to toxic levels.…”

Section: Introductionmentioning

confidence: 99%

“…As explained by Daskalopoulou et al, [28] the main mechanism of drug interaction occurs through the action of RD on the hepatic cytochrome p450 complex of enzymes, the nature and extent of which are yet to be fully understood. Even in the absence of potential RD-ART interactions, the negative consequences of RD use among PLHIV have been well documented [33][34][35][37][38][39][40][41][42]. For example, in their meta-analysis of contemporary research,…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Yes to Recreational Drugs and Complementary Medicines But No to Life-Saving Medications: Beliefs Underpinning Treatment Decisions Among PLHIV

et al. 2019

View full text Add to dashboard Cite

Despite the life-preserving benefits of antiretroviral therapy (ART), some people living with HIV (PLHIV) delay, decline or diverge from recommended treatment while paradoxically being willing to use potentially dangerous substances, such as recreational drugs (RD) and complementary medicines (CM). During 2016 and 2017, interviews were conducted with 40 PLHIV, in Australia to understand drivers underpinning treatment decisions. While many believed ART to be effective, they expressed concerns about long-term effects, frustration over perceived lack of autonomy in treatment decisions and financial, emotional and physical burdens of HIV care. In contrast, they ascribed a sense of self-control over the use of RD and CM, along with multiple professed benefits. The perceived burden of ART emerged as a motivator for deviating from recommended treatment, while positive views towards RD and CM appear to justify use. This study may serve as guidance for the development of future strategies to address barriers to treatment uptake and adherence and subsequently health outcomes for PLHIV in Australia and elsewhere.

show abstract

“…methamphetamine, mephedrone and GHB‐gamma hydroxybutyrate) before or during sexual activity [ 4 , 5 ]. Such behaviours are typically associated with condomless anal intercourse (CAI) between serodiscordant partners in the absence of biomedical prevention technologies, group sex, higher numbers of sex partners and the sharing of injecting equipment [ 6 , 7 ]. The reported prevalence of SDU among MSM varies by geography and recall period.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of sexualized drug use and risk of HIV among sexually active MSM in East and South Asian countries: systematic review and meta‐analysis

et al. 2023

View full text Add to dashboard Cite

Introduction Sexualized drug use (SDU), the use of psychoactive drugs in the context of sexual intercourse, has been identified as a risk factor for HIV among men who have sex with men (MSM) in Asia. Given the distinct social and cultural context of same‐sex relationships and drug‐using practice in Asia, we aimed to describe the prevalence of SDU in East and South Asian countries and its associations with condomless anal sex (CAI) and HIV status. Synthesizing SDU research in this region, including SDU definitions, prevalence and outcomes, provides insights to inform future research and improved programme planning, resourcing and advocacy. Methods We systematically searched OVID Medline, OVID EMBASE, OVID Global Health, CINAHL, PsycINFO and SCOPUS publication databases for scientific articles published from 1990 to 2022 measuring SDU among MSM in East and South Asian countries. A narrative synthesis was utilized to describe key study attributes and findings, and meta‐analyses using random pooled effect models were used to estimate SDU prevalence and its associations with CAI and HIV status. Subgroup meta‐analyses, sensitivity analysis and assessment of publication bias examined potential sources of heterogeneity for the pooled SDU prevalence estimates. Results and discussion Of the 1788 publications screened, 49 publications met the selection criteria and 18 were suitable for meta‐analyses. Findings highlight SDU definitions distinct from other regions but inconsistencies in the definition of SDU between studies that have been highlighted in research elsewhere. The pooled prevalence of recent SDU (past 12 months) was 13% (95% CI = 10–16%; I 2 = 97.6) but higher when studies utilized self‐administered surveys (15%; 95% CI = 12–19%; p <0.05). SDU was associated with greater odds of CAI (pooled odds ratio [OR] = 3.21; 95% CI = 1.82–5.66) and living with diagnosed HIV (OR = 4.73; 95% CI = 2.27–8.21). Conclusions SDU is common among MSM in East and South Asian countries, but varying SDU definitions limit between‐study comparisons. Responses to SDU‐related harms should consider local contexts, including specific drug types used and their relative risks.

show abstract

Hidden dangers among circuit parties—A systematic review of HIV prevalence, sexual behaviors and drug abuse during the biggest gay events

Cited by 10 publications

References 15 publications

Impact of MenB Vaccination on Neisseria gonorrhoeae infections: a comprehensive state-of-the-art review

Impact of MenB Vaccination on Neisseria gonorrhoeae infections: a comprehensive state-of-the-art review

Yes to Recreational Drugs and Complementary Medicines But No to Life-Saving Medications: Beliefs Underpinning Treatment Decisions Among PLHIV

Prevalence of sexualized drug use and risk of HIV among sexually active MSM in East and South Asian countries: systematic review and meta‐analysis

Contact Info

Product

Resources

About