Hidradenitis Suppurativa of the Adult and Its Management

Hidradenitis suppurativa: A comprehensive review

“…In older studies, bacteria were collected from the surfaces of HS lesions. 11,[59][60][61] Samples were prone to contamination with skin flora.…”

“…4,11,[59][60][61][62] Gram-negative bacteria, such as Escherichia coli, Klebsiella, and Proteus, may be more common in perineal HS. 30,63 Chlamydia trachomatis was demonstrated serologically in 6 of 7 patients with perineal HS but was absent in the pus of examined lesions.…”

“…A retrospective study of 45 patients showed that 10 had a history of mechanical irritation before onset of the disease. 61 The mentioned causes of trauma were diverse, and ranged from shaving to friction from a prosthesis. 61 Mustafa et al 8 reported several patients whose HS was worsened by the use of antiperspirants.…”

“…61 The mentioned causes of trauma were diverse, and ranged from shaving to friction from a prosthesis. 61 Mustafa et al 8 reported several patients whose HS was worsened by the use of antiperspirants. 8 Some authors have suggested that antiperspirants could exacerbate HS by causing an occlusive film over axillary skin.…”

“…4 A retrospective study by Morgan and Leicester 66 comparing 40 HS patients with 40 age-matched controls demonstrated no significant differences in shaving, chemical depilatories, deodorants, and talcum powder application in both axillary and inguinal regions, as previously suggested. 3,4,11,29,39,61 Older papers suggest that poor hygiene, dyspepsia, constipation, and hemorrhoids could potentially contribute to HS; none of these causes have been proven. 3,8 Obesity may serve to retain sweat, possibly aggravating the role of perspiration as an irritant in HS.…”