I reviewed the literature about past and current methods of subunit inference and about the involvement of subunits in direction selectivity, I contributed to writing the manuscript, and prepared the figures Figure 1, Figure 2, and Figure 3. SN reviewed the literature about subunit function and adaptation, contributed to writing the manuscript, and prepared the figures Figure 4, Figure 5, and Figure 6. TG supervised the literature research and prepared the initial draft. All authors helped revise the manuscript.