High amounts of SARS-CoV-2 in aerosols exhaled by patients with Omicron variant infection

Zheng, Jing; Wang, Zhongyi; Li, Jiaming; Zhang, Yidun; Jiang, Lina; Fu, Yingying; Jin, Y. J.; Cheng, Hongliang; Li, Jingjing; Chen, Zehui; Tang, Fei; Lu, Bing; Li, Li; Zhang, Xiaopeng

doi:10.1016/j.jinf.2022.02.015

Cited by 30 publications

(31 citation statements)

References 8 publications

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“…We read with interest the article of Zheng et al [1] , who reported that a high breath emission rate of viral particles may be one of the most important reasons for justifying the higher transmissibility of the new severe acute respiratory coronavirus 2 (SARS-CoV-2) Omicron variant. Unfortunately, no direct comparison of viral load with previous SARS-CoV-2 variants has been reported in the work of Zheng et al, so that this conclusion remains intriguingly speculative.…”

mentioning

confidence: 99%

SARS-CoV-2 Omicron infection is associated with high nasopharyngeal viral load

Salvagno

Henry

Pighi

et al. 2022

Journal of Infection

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mentioning

confidence: 99%

SARS-CoV-2 Omicron infection is associated with high nasopharyngeal viral load

Salvagno

Henry

Pighi

et al. 2022

Journal of Infection

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“…The role of superspreading events further suggests that aerosol transmission contributes to the pandemic 7 . It was recently found that the newly emerged variants of concern show increased infectivity and further confirming the importance of aerosol-mediated spread 8 – 10 .…”

Section: Introductionmentioning

confidence: 75%

SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients

Kurver¹,

Kieboom

Lanke

et al. 2022

Sci Rep

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Knowledge about contagiousness is key to accurate management of hospitalized COVID-19 patients. Epidemiological studies suggest that in addition to transmission through droplets, aerogenic SARS-CoV-2 transmission contributes to the spread of infection. However, the presence of virus in exhaled air has not yet been sufficiently demonstrated. In pandemic situations low tech disposable and user-friendly bedside devices are required, while commercially available samplers are unsuitable for application in patients with respiratory distress. We included 49 hospitalized COVID-19 patients and used a disposable modular breath sampler to measure SARS-CoV-2 RNA load in exhaled air samples and compared these to SARS-CoV-2 RNA load of combined nasopharyngeal throat swabs and saliva. Exhaled air sampling using the modular breath sampler has proven feasible in a clinical COVID-19 setting and demonstrated viral detection in 25% of the patients.

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“… 2 Araf Y et al [ 13 ] This study discussed the genomics and transmission of omicron as well as effectiveness of vaccine against this new variant of covid-19, omicron. 3 Zheng J et al [ 14 ] High transmission of omicron variant via aerosols of infected patients 4 Cheng VC-C et al [ 15 ] Omicron variant is transmitted through airborne route and can be effectively controlled by increased indoor dilution of air. 5 Mohapatra RK et al [ 16 ] Contaminated air associated with omicron variant with high transmission rate poses a challenge to control its spread.…”

Section: Future Prospectsmentioning

confidence: 99%