High and low Fc IgG-receptor expression in human chronic granulocytic leukaemia cells

Harłozińska, A; Potomski, J; Lawińska, B; Noworolska, A; Richter, R. L.

doi:10.1038/bjc.1982.33

Br J Cancer

1982

DOI: 10.1038/bjc.1982.33

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High and low Fc IgG-receptor expression in human chronic granulocytic leukaemia cells

A Harłozińska¹,

J Potomski²,

B Lawińska³

et al.

Abstract: Summary.-Discontinuous density-gradient centrifugation was used to separate chronic granulocytic leukaemia (CGL)

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1985

1992

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Cited by 5 publications

References 11 publications

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Expression of nonspecific cross-reacting antigen species in myeloid leukemic patients and healthy subjects

Noworolska

Harłozińska

Buchegger

et al. 1989

Blut

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The reactivity of two monoclonal antibodies recognizing NCA-95 and NCA-55 (MAb 47 and MAb 192, respectively) with a polyclonal anti-NCA serum in myeloid leukemic cells isolated by density gradient centrifugation was compared using an immunofluorescence test (IF). It was observed that the blood myeloid cells in 78.8% of the patients with different types of myelocytic leukemias and all granulocytes of 15 normal donors showed similar expression of the NCA species studied. The leukocytes of the remaining patients did not synthesize the NCA-95 species regardless of the maturation stage of the cells studied. In two patients, synthesis of this NCA form was limited to the fractions containing myelocytes and metamyelocytes. We have found that all anti-NCA antibodies studied recognized different antigenic epitopes in a myeloid cell series. A relationship between the patient's survival and the proportion of NCA-containing cells was also observed.

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Expression of nonspecific cross-reacting antigen species in myeloid leukemic patients and healthy subjects

Noworolska

Harłozińska

Buchegger

et al. 1989

Blut

View full text Add to dashboard Cite

show abstract

FcRIII (CD16) expression on neutrophils from chronic myeloid leukemia. A flow cytometric study

et al. 1992

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Non-specific cross-reacting antigen (NCA) in individual maturation stages of myelocytic cell series

Noworolska¹,

Harłozińska²,

Richter³

et al. 1985

Br J Cancer

Self Cite

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High and low Fc IgG-receptor expression in human chronic granulocytic leukaemia cells

Abstract: Summary.-Discontinuous density-gradient centrifugation was used to separate chronic granulocytic leukaemia (CGL)

Cited by 5 publications

References 11 publications

Expression of nonspecific cross-reacting antigen species in myeloid leukemic patients and healthy subjects

Expression of nonspecific cross-reacting antigen species in myeloid leukemic patients and healthy subjects

FcRIII (CD16) expression on neutrophils from chronic myeloid leukemia. A flow cytometric study

Non-specific cross-reacting antigen (NCA) in individual maturation stages of myelocytic cell series

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