Qompsell are extracts of several traditional Chinese medicines: Astragalus membranaceus, Portulaca oleracea L, Flavescent sophora and Andrographis paniculata, etc. The macrophage phagocytic activity, macrophage ROS (reactive oxygen species), activity of serum lysozyme, SOD (superoxide dismutase), NOS (nitric oxide synthetase) and levels of total serum protein, globulin, and albumin were measured in carp that had been fed diets containing Qompsell at 0.3 g kg−1 for 60 days. The results showed that Qompsell had increased the macrophage phagocytic activity, macrophage ROS and the content of total protein, globulin, lysozyme in serum significantly (P<0.05). Also, the triglyceride and cholesterol levels had slightly increased but there was no significant difference. However, NOS, SOD and albumin showed no significant difference (P>0.05). These results indicate that the Qompsell formula might elevate the immunity function of carp (Cyprinus carpio).