2004
DOI: 10.1016/s0360-3016(03)01494-9
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High-dose-rate intraoperative radiotherapy for close or positive margins in patients with locally advanced or recurrent rectal cancer

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Cited by 78 publications
(49 citation statements)
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“…This finding could be attributed to lack of power but could also be partly attributed to an effect of PDR-BT being able to compensate for an R1 resection because, in the first two years after surgery, the local control was similar between R0 and R1 resection (Figure 2(c)). Furthermore, the five-year local control rate of 32% after R1 resection is good compared to other studies [10,12,14,22,23]. This is further supported by the observation that the number of catheters significantly influenced the possibility of achieving local control.…”
Section: Discussionsupporting
confidence: 60%
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“…This finding could be attributed to lack of power but could also be partly attributed to an effect of PDR-BT being able to compensate for an R1 resection because, in the first two years after surgery, the local control was similar between R0 and R1 resection (Figure 2(c)). Furthermore, the five-year local control rate of 32% after R1 resection is good compared to other studies [10,12,14,22,23]. This is further supported by the observation that the number of catheters significantly influenced the possibility of achieving local control.…”
Section: Discussionsupporting
confidence: 60%
“…Nuyttens et al reported a significant difference in local control between primary and recurrent disease in only 37 patients (p ¼ .042) using HDR-BT [12]. Selection bias and the limited number of patients involved in all three studies are likely explain this difference.…”
Section: Discussionmentioning
confidence: 92%
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