High-Efficiency Control of Gray Mold by the Novel SDHI Fungicide Benzovindiflupyr Combined with a Reasonable Application Approach of Dipping Flower

Abstract

In this study, a novel succinate dehydrogenase inhibitor (SDHI) fungicide benzovindiflupyr was found to have strong inhibitory activity against gray mold caused by Botrytis cinerea. The sensitivity of B. cinerea to benzovindiflupyr was determined by testing 103 pathogen isolates with mean values of 2.15 ± 0.19 mg L and 0.89 ± 0.14 mg L for mycelial growth and spore germination inhibition, respectively. Furthermore, benzovindiflupyr had excellent long-lasting protective activity. Unfortunately, there were positive correlations between benzovindiflupyr and boscalid ( r = 0.3, P = 0.04) and between benzovindiflupyr and isopyrazam ( r = 0.31, P = 0.04). In the field, cucumber flowers are susceptible to infection by B. cinerea. Benzovindiflupyr applied at 20 mg L by dipping flowers could successfully control cucumber gray mold, with the benzovindiflupyr dose of dipping flower application less than 1% of that of spraying application. Benzovindiflupyr combined with dipping flower application showed significant control of gray mold.

Synthesis and Biological Activity of Novel Succinate Dehydrogenase Inhibitor Derivatives as Potent Fungicide Candidates

“…General Synthesis Procedure for Target Compound (5). In a 100 mL one-neck round-bottom flask, 3 mL of compound 3 was added and dissolved in 30 mL of dry CH 2 Cl 2 .…”

“…Plant diseases cause a dramatic decline in crop quality and yield, as a result of which farmers suffer huge economic losses. , Treating crops with fungicides having different modes of action against plant disease damage is very necessary . Succinate dehydrogenase (SDH) inhibitors are widely used to protect crops from all kinds of plant pathogen attacks. − As an important membrane complex in the tricarboxylic acid cycle in the mitochondrial respiratory chain, SDH is an ideal fungicide target. , SDHIs disrupt the respiration of the pathogen and inhibit its growth by inhibiting the oxidation of succinate to fumarate, thus causing pathogen death. , …”

Discovery of Natural Rosin Derivatives Containing Oxime Ester Moieties as Potential Antifungal Agents to Control Tomato Gray Mold Caused by Botrytis cinerea

“…Gray mold (caused by Botrytis cinerea (B. cinerea)) is a fungal disease that can reduce the yield of many important agricultural crops, such as tomatoes, strawberries, and grapes. 1 For example, gray mold disease in tomato mainly occurs in its flowering and fruiting period, and the disease can prevent the healthy growth of plants, reduce their yield and quality, and even harm tomatoes during the postharvest storage period. According to statistical analyses, 20−30% of tomatoes are lost to gray mold every year, and that figure is even as high as 50% in severe cases.…”

Synthesis and fungicidal activity of novel benzimidazole derivatives bearing pyrimidine‐thioether moiety against Botrytis cinerea

“…Gray mold elicited by Botrytis cinerea, is a serious plant fungal disease, and infects a lot of vegetables and fruits like tomato, cucumber, pepper, grape, apple and strawberry. 1,2 In these crops, leaves, stems, flowers and fruits are prone to infection, which results in dramatic yield reduction and considerable quality degradation. 3 At present, the main strategy to protect the crops from B. cinerea is chemical control, including the application of effective fungicides such as carbendazim, pyrimethanil, fludioxonil, boscalid and iprodione.…”