2008
DOI: 10.2109/jcersj2.116.320
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High energy irradiation--a tool for enhancing the bioactivity of Hydroxyapatite

Abstract: The effect of swift heavy ion irradiation on the surface modification and bioactivity of microwave sintered hydroxyapatite (HAp) pellets has been studied. The irradiated surface of the pellets was completely covered by tightly packed rectangular platy crystals. The pellets subjected to 300°C conventional sintering (after microwave sintering) before irradiation showed a plain surface. XRD studies confirmed the surface to be HAp but decrease in crystallinity and crystal size was observed. In vitro bioactivity st… Show more

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Cited by 37 publications
(18 citation statements)
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“…Normally, the formation of a dense apatite layer is observed on porous bioactive materials from SBF solution, but the formation of porous interlinked apatite layer from SBF is rarely reported. These porous apatite layers can enhance the osteointegration and osteoconduction properties [17]. This kind of activity shows that after incubation in SBF, HAp pellets When a material is incubated in SBF solution, the formation of apatite layer on the surface of pellet goes through a sequence of chemical reactions like spontaneous precipitation, nucleation and growth of calcium phosphate [18].…”
Section: Resultsmentioning
confidence: 99%
“…Normally, the formation of a dense apatite layer is observed on porous bioactive materials from SBF solution, but the formation of porous interlinked apatite layer from SBF is rarely reported. These porous apatite layers can enhance the osteointegration and osteoconduction properties [17]. This kind of activity shows that after incubation in SBF, HAp pellets When a material is incubated in SBF solution, the formation of apatite layer on the surface of pellet goes through a sequence of chemical reactions like spontaneous precipitation, nucleation and growth of calcium phosphate [18].…”
Section: Resultsmentioning
confidence: 99%
“…Interestingly bioactivity of HA bioceramics might be enhanced by a high-energy ion irradiation [640]. The effect was attributed to formation of a unique 3D macroporous apatite layer of decreased crystallinity and crystal size on the irradiated surfaces.…”
Section: Bioactivitymentioning
confidence: 99%
“…Vallet Regi and Daniel Arcos have reported Si substituted HA is among the most interesting bioceramics from the bioactivity point of view [37]. Surface modification by swift heavy ion irradiation was found to enhance the bioactivity of HA [38]. HA is known to be bioactive and bioresorbable but the rate is too low while calcite is highly biodegradable.…”
Section: Discussionmentioning
confidence: 99%