2007
DOI: 10.1002/bdra.20369
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High fever–related maternal diseases as possible causes of multiple congenital abnormalities: A population‐based case‐control study

Abstract: An association was found between high fever-related maternal diseases and a higher risk for MCAs; however, a certain portion of these MCAs is preventable by antifever therapy.

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Cited by 33 publications
(25 citation statements)
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“…Recently, Czeizel et al reported that some acute maternal diseases might be associated with multiple congenital abnormalities, including cardiovascular congenital abnormalities, and the common teratogenic factor of these maternal diseases may be the high fever. 7 Thus, the patient's mother having had fever during pregnancy on the fourth month may be a risk factor for some acute maternal diseases; however, we did not find a significant association between the fever and IE in our case. Therefore, a possible association between maternal fever and neonatal IE needs further studies.…”
Section: An Unusual Cause Of Early Respiratory Distress In a Neonate:contrasting
confidence: 54%
“…Recently, Czeizel et al reported that some acute maternal diseases might be associated with multiple congenital abnormalities, including cardiovascular congenital abnormalities, and the common teratogenic factor of these maternal diseases may be the high fever. 7 Thus, the patient's mother having had fever during pregnancy on the fourth month may be a risk factor for some acute maternal diseases; however, we did not find a significant association between the fever and IE in our case. Therefore, a possible association between maternal fever and neonatal IE needs further studies.…”
Section: An Unusual Cause Of Early Respiratory Distress In a Neonate:contrasting
confidence: 54%
“…In contrast, several other studies observed reductions in risk with antipyretic medication. 34,35,[38][39][40]42,46,47 In some cases, the risk associated with fever was even eliminated. 35,36,40…”
Section: Antipyretic Medicationmentioning
confidence: 99%
“…[1][2][3] Several studies have demonstrated that in women with influenza, prompt antiviral use reduces maternal mortality and adverse pregnancy outcomes, 8,9 although a small study using health registry data demonstrated an increased risk of late transient hypoglycaemia in infants exposed in utero.…”
Section: Discussionmentioning
confidence: 99%
“…3 Pregnant women were therefore identified as a high risk group requiring early treatment or post-exposure antiviral prophylaxis with the neuraminidase inhibitors zanamivir or oseltamivir during the 2009 Influenza A/ H1N1 pandemic. 1,4 Oseltamivir is administered orally and is readily absorbed from the gastrointestinal tract, whereas zanamivir is an inhaled preparation and as such has lower systemic and subsequent transplacental bioavailability.…”
Section: Introductionmentioning
confidence: 99%