High-Frequency Contrast Harmonic Imaging of Ophthalmic Tumor Perfusion

Schlottmann, Klaus; Fuchs-Koelwel, B; Demmler-Hackenberg, Martina; Gabel, Virginie; Schölmerich, Jürgen

doi:10.2214/ajr.184.2.01840574

Cited by 8 publications

(2 citation statements)

References 13 publications

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“…Use of alternate ultrasonographic techniques may be indicated, including Doppler ultrasonography and contrast techniques such as contrast harmonic imaging. The use of contrast harmonic imaging has been described for examination of eyes of humans 33 and other animals. 34 Results of another study 34 indicate contrast-enhanced ultrasonography is 100% accurate for the detection of retinal detachment and differentiation between that problem and vitreous cavity membranes.…”

Section: Discussionmentioning

confidence: 99%

Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000–2010)

Gallhoefer¹,

Bentley

Ruetten

et al. 2013

javma

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Agreement between tests evaluated in this study was clinically satisfactory for identification of intraocular neoplasia. Typically, diseases were misdiagnosed via ultrasonography for eyes with poor image contrast. Because determination of ultrasonographic diagnoses of retinal detachment and intraocular neoplasm may be of prognostic importance, performance of additional ultrasonographic techniques may be indicated.

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Section: Discussionmentioning

confidence: 99%

Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000–2010)

Gallhoefer¹,

Bentley

Ruetten

et al. 2013

javma

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“…Compared with MRI, CEUS has many advantages, including no nephrotoxicity, a low risk of allergy, no radioactivity, easy application, and real‐time observation 18 . However, there are few reports about CEUS applied in orbital space‐occupying lesions, and quantitative analysis of CEUS is lacking 19–21 …”

Section: Discussionmentioning

confidence: 99%

Differentiation of Malignant and Benign Orbital Space‐Occupying Lesions Using Contrast‐Enhanced Ultrasound

Zhang

Deng

Sun

et al. 2021

J of Ultrasound Medicine

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Objectives To evaluate the value of time‐intensity curve (TIC) analysis of contrast‐enhanced ultrasound (CEUS) signal to differentiate malignant from benign orbital space‐occupying lesions. Methods The CEUS signal of 111 patients with orbital space‐occupying lesions was retrospectively analyzed using SonoLiver software. TIC‐related parameters such as the arrival time (AT), rise time (RT), time to peak (TTP), maximum intensity (IMAX), mean transit time (mTT), slope of the increase (RS), and slope of the decrease (DS) were compared between the malignant and benign groups. Receiver operating characteristic (ROC) curve analysis was used to acquire the cutoff values of these parameters for differential diagnosis. Results TIC patterns were characterized by fast increase and fast decrease in signal intensity in the malignant group, fast increase and a slow decrease in signal intensity in the benign group. The differences in the IMAX, RS, DS, mTT, TTP, and RT between the 2 groups were statistically significant (p <.01), while the difference in the AT were not (p = .672). ROC curve analysis showed that IMAX = 427.20, DS = 34.72, and mTT = 33.55 were the best cutoff values for differential diagnosis of malignant and benign space‐occupying lesions. The accuracy rate of CEUS visual evaluation for differential diagnosis was 66.67% (74/111), while TIC quantitative analysis could effectively improve the accuracy to 89.19% (99/111). Conclusions TIC analysis can improve CEUS efficiency to differentiate malignant from benign orbital space‐occupying lesions.

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Intravenous Contrast-Enhanced Bowel Ultrasound

Schacherer¹

2012

Ultrasound of the Gastrointestinal Tract

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High-Frequency Contrast Harmonic Imaging of Ophthalmic Tumor Perfusion

Cited by 8 publications

References 13 publications

Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000–2010)

Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000–2010)

Differentiation of Malignant and Benign Orbital Space‐Occupying Lesions Using Contrast‐Enhanced Ultrasound

Intravenous Contrast-Enhanced Bowel Ultrasound

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