High hydrostatic pressure in food industry applications

High pressure initiated solvent and catalyst-free instant Paal–Knorr reactions

“…the food industry large (often ton) scale equipment is available thus the industrial level scale up of synthetic applications is within reach. 22 The Barocycler 2320EXT instrument, that has been used in this study, has a 20 mL pressure chamber, and it could conveniently accommodate the 5 mL polyethylene vial heat-sealed before the reaction (Fig. SI 4 †).…”