High-intensity endurance training improves adiponectin mRNA and plasma concentrations

Abstract

Adiponectin is an anti-inflammatory protein that reduced in obesity. Exercise training may reduce the adipose tissue (AT), although it is not well known whether exercise-induced change in AT, increases the adiponectin mRNA expression and plasma concentrations or not; therefore, the purpose of this study was to investigate the adiponectin mRNA and plasma concentrations in middle-aged men after 12 weeks high-intensity exercise training and after a week detraining. Sixteen sedentary overweight and obese middle-aged men (age 41.18 ± 6.1 years; ± SD) volunteered to participate in this study. The subjects were randomly assigned to training group (n = 8) or control group (n = 8). The training group performed endurance training 4 days a week for 12 weeks at an intensity corresponding to 75-80% individual maximum oxygen consumption for 45 min. After 12 weeks of training, subjects underwent a week of detraining. The results showed that the BMI as well as central and peripheral AT volume were decreased in the training group compared to the control group (P < 0.05). After 12 weeks, the training group resulted in a significant increase (P < 0.05) in the adiponectin gene expression in abdominal and gluteal subcutaneous AT when compared with the control group. The results showed that plasma adiponectin concentrations increased and insulin resistance decreased after training compared to the control group (P < 0.05). After a week of detraining, the variables were not changed significantly in the training group. In conclusion, high-intensity endurance training caused an increase adiponectin mRNA in obese middle-aged men.

Efeito do treinamento concorrente e destreinamento sobre o biomarcador anti-inflamatório e níveis de condicionamento físico em crianças obesas

“…After the training program, the serum adiponectin concentrations were increased in both groups 31 . long-term training (≥ 12 weeks) -Moghadasi et al 12 investigated the mrNA adiponectin and plasma concentrations in middleaged overweighed and obese men after high-intensity physical training of 12 weeks (4 d/w) with 75-80% of individual maximum oxygen consumption for 45 min and after one week of detraining. The results showed that the plasma adiponectin concentrations increased after training in the experimental group compared with the control group (p< 0.05).…”

“…Tere are some reports that exercise may lead to increase of the adiponectin levels 12,13 , while others did not present any alteration in the adiponectin concentrations 14,15 . little is known about the alterations of the adiponectin levels during puberty and even less information about the detraining role after physical training on physical fitness as well as about the levels of adiponectin in the blood plasma of obese children.…”

Decrease in regional body fat after long-term high-intensity interval training

“…Thus far, however, there has been no consensus as to the effect of exercise on serum adiponectin concentration, which has been reported to decrease 22,23) , increase 5,6,24) , and remain unchanged 7,25) with exercise.…”

“…Several studies have shown significant increases in serum adiponectin concentration after high-intensity training 5,6,24) . However, in those studies, increases in adiponectin level were almost always accompanied by loss of fat mass 5,6,24) .…”

“…It has been suggested that, even with a significantly smaller exercise volume, high-intensity exercise has a more favorable effect on fat loss than does continuous moderate-intensity exercise 2,3) . Few studies, however, have examined the effect of long-term HIIT on body composition [4][5][6][7] . Trapp et al showed that HIIT had a significant reduction in fat mass and trunk fat, compared with energy-matched, longer-duration continuous endurance training among young women.…”