High molecular weight persimmon tannin is a potent antioxidant both ex vivo and in vivo

Tian, Yun; Zou, Bo; Li, Chunmei; Yang, Jie; Xu, Shengyu; Hagerman, Ann

doi:10.1016/j.foodres.2011.10.005

Cited by 67 publications

(34 citation statements)

References 38 publications

(44 reference statements)

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“…No que tange à aplicação terapêutica, os taninos são conhecidos por sua atividade antioxidante in vivo e ex vivo e atividade hipocolesterolêmica (TIAN et al, 2012), protegendo os tecidos da peroxidação lipídica. Inúmeras atividades biológicas estão associadas aos flavonoides, como funções antioxidante, anti-inflamatória e anticancerígena (KSOURI et al, 2013), enquanto que os depsídeos e depsidonas apresentam propriedades antioxidantes (CHOMCHEON al., 2009), analgésicas e antipiréticas (OKUYAMA et al, 1995).…”

Section: Resultsunclassified

Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'

et al. 2015

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Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'. 329Ciência Rural, v.45, n.2, fev, 2015.Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'Chemical and phytochemical composition of flours from skin and seeds of 'Bengal' lychee (Litchi chinensis Sonn)

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Section: Resultsunclassified

Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'

et al. 2015

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“…Polyphenols have attracted much attention due to their health beneficial effects such as antioxidant, anti-inflammatory, antiobesity and hypolipidemic effects (Lin et al, 2007;Tian et al, 2012;Zou et al, 2014). Our previous work suggested that persimmon tannin inhibited hepatic lipid accumulation in rats through activating adenosine-monophosphate-activated protein kinase (AMPK) (Zou et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Persimmon tannin alleviates hepatic steatosis in L02 cells by targeting miR-122 and miR-33b and its effects closely associated with the A type ECG dimer and EGCG dimer structural units

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Zeng

et al. 2014

Journal of Functional Foods

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“…The CT from common forages such as L. corniculatus, L. pedunculatus, and O. viciifolia contain a varying mixture of PC and PD subunits, increasing the complexity of the CT (Table 1, Columns E and F). To add to the complexity, CT structures isolated from some sources, such as Vitis or Diospyros (Tian et al 2012), are found to contain a derivatized C3 hydroxyl group as the gallate ester. This may occur multiple times and at any point along the oligomer/polymer chain.…”

Section: Limitations and Future Directionsmentioning

confidence: 99%

The role of condensed tannins in ruminant animal production: advances, limitations and future directions

et al. 2017

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-Tannins represent one of the most abundant polyphenolic compounds in plants. Tannins exist as a multitude of chemically unique entities in nature. The most commonly occurring tannins are typically divided into two major classes based on chemical structure: hydrolysable (HT) or condensed tannins (CT). Hydrolysable tannins are esters of gallic or ellagic acid linked to a polyol core, typically glucose. Condensed tannins or proanthocyanidins consist of flavan-3-ol subunits linked together to form oligomers and polymers. Both HT and CT are defined as astringent, medium-to-high-molecular weight polyphenolic compounds that characteristically bind and precipitate soluble proteins. The objective of this paper was to present recent advances in CT-ruminant interactions, the limitations associated with understanding and using CT in ruminant animal production, and future needs for research to further advance our knowledge of the role of CT in optimization of ruminant animal production. Condensed tannins pose some anti-nutritional problems to ruminants due to their astringent property that reduces feed intake and, consequently, animal performance. Ruminants can, however, tolerate CT by slowly adapting the ruminal microbes to the toxic effects of CT and by releasing CT-binding salivary proteins. The protein-binding ability of CT has some benefits to the ruminant due to complexes formed with essential amino acids, preventing their degradation in the rumen, but releasing them in the lower gut for absorption by the animal. Recent data have suggested increased N retention when CT is given to growing animals. There are potential benefits of using CT and HT for anthelmintic purposes due to their ability to inhibit egg hatching and larval motility of gastrointestinal nematode parasites, especially in small ruminants. Condensed tannins also bind to minerals (Al, Ca, Co, Cu, Fe, Mg, Mn, P, and Zn). Although studies with ruminants have been contradictory, it has been reported that because the CT-metal ion complex is stable over a wide pH range, CT may reduce the bioavailability of minerals. Methane mitigation by feeding CT might be the most impactful benefit for ruminant production. Many empirical equations have been developed to predict ruminal methane emissions, but very few have included CT. Future research should focus on the improvement of methodology to assess CT biological activity, interaction with other plant-specialized metabolites, and associated physiological and nutritional impacts on ruminants.

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High molecular weight persimmon tannin is a potent antioxidant both ex vivo and in vivo

Cited by 67 publications

References 38 publications

Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'

Composição química e fitoquímica das farinhas da casca e da semente de lichias (Litchi chinensis Sonn) cultivar 'Bengal'

Persimmon tannin alleviates hepatic steatosis in L02 cells by targeting miR-122 and miR-33b and its effects closely associated with the A type ECG dimer and EGCG dimer structural units

The role of condensed tannins in ruminant animal production: advances, limitations and future directions

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