High-performance liquid chromatographic determination of ciprofloxacin in plasma samples

Vybíralová, Zuzana; Nobilis, Milan; Zoulová, J; Kvĕtina, J; Petr, P.

doi:10.1016/j.jpba.2004.09.034

Cited by 93 publications

(45 citation statements)

References 26 publications

(102 reference statements)

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“…HPLC is widely employed for the determination of CIP and NOR either in biological fluids, edible animal products, feed and pharmaceutical formulations (Barbosa, Berges, Sanz-Nebot, 1996;Belal, Al-Majed, Al-Obaid, 1999;Budvari-Barany et al 1991;Córdoba-Borrego, Cordoba-Diaz, Cordoba-Diaz, 1999;Husain et al 1995;Kirkland, Mccombs, Kirkland, 1994;Lacroix, Curran, Sears, 1996;Morley, Erold, 1993;Samanidou, Christodoulou, Papadoyannis, 2005;Sowinski, Kays, 2004;Thoppil, Amin, 2000;Tiefenbacher et al 1994;Torniainen, Tammilehto, Ulvi, 1996;Vybiralova et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Quantitative determination of ciprofloxacin and norfloxacin in pharmaceutical preparations by high performance liquid chromatography

Kassab¹,

Singh²,

Kedor-Hackmam³

et al. 2005

Rev. Bras. Cienc. Farm.

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Section: Introductionmentioning

confidence: 99%

Quantitative determination of ciprofloxacin and norfloxacin in pharmaceutical preparations by high performance liquid chromatography

Kassab¹,

Singh²,

Kedor-Hackmam³

et al. 2005

Rev. Bras. Cienc. Farm.

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“…CIP is also used to treat or prevent anthrax in people who may have been exposed to anthrax germs in the air [1-3]. High performance liquid chromatography [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22], high performance thin layer chromatography [23,24], spectrofluorimetry [25], atomic absorption spectrometry [26], Rayleigh light scattering technique [27] have been utilized for the determination of ciprofloxacin, but complicated preconcentration or multi-solvent extraction technique is also couple with these technique due to the complexity of the real samples and the low concentration of the analyte.…”

Section: Introductionmentioning

confidence: 99%

Anodic Voltammetry of Ciprofloxacin and its Analytical Applications

Uslu

Bozal²,

Kuscu³

2010

TOCBMJ

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Abstract:The electrooxidative behavior and determination of ciprofloxacin at a glassy carbon electrode were investigated using cyclic, linear sweep, differential pulse and square wave voltammetric techniques. The dependence of the peak current and peak potentials on pH, concentration, nature of buffer, and scan rate were examined. The oxidation of ciprofloxacin gave a single and irreversible peak at glassy carbon electrode. The process was diffusion controlled. A linear response was obtained between 1.0 10 -6 and 4.0 10 -5 M in 0.1 M sulphuric acid for both techniques. The recovery studies were also achieved to check selectivity and accuracy of the methods. The proposed methods were applied for the determination of ciprofloxacin from pharmaceutical dosage forms without any time-consuming extraction, separation, adsorption steps. The repeatability, reproducibility, precision and accuracy of the proposed methods were investigated.

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“…Highperformance liquid chromatography (HPLC) has become an important tool for the analysis of single and various combinations of quinolones in biological fluids, foods, environmental samples and pharmaceutical preparations using either UV or fluorescence as the detection method [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Separation and Determination of Quinolones in Pharmaceuticals by Micellar Liquid Chromatography

Collado-Sánchez

Rambla-Alegre

Carda‐Broch

et al. 2010

Journal of Liquid Chromatography & Related Technologies

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A rapid and simple liquid chromatographic procedure using micellar mobile phases is reported for the separation and determination of four quinolones (pipemidic acid, levofloxacin, norfloxacin and moxifloxacin) in pharmaceuticals.This purpose was achieved without any previous pretreatment step in a C18 column using a micellar mobile phase of 0.15 M sodium dodecyl sulphate, 2.5% propanol and 0.5% triethylamine at pH 3, with retention times below 12 min. For detection, the diode-array UV-Vis set at 276 nm was used. The limits of detection and quantification were between 8-51 and 28-171 ng/mL, respectively. This method was validated in terms of intra-day and inter-day precision and accuracy, and robustness. Calibration curves over the concentration range of 0.1-50 g/mL were linear (r 2 > 0.9997) and. Good claim percentages (96-106 %) were obtained in the analysis of pharmaceutical formulations. The results show that the procedure is suitable for the routine analysis of drugs.

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High-performance liquid chromatographic determination of ciprofloxacin in plasma samples

Cited by 93 publications

References 26 publications

Quantitative determination of ciprofloxacin and norfloxacin in pharmaceutical preparations by high performance liquid chromatography

Quantitative determination of ciprofloxacin and norfloxacin in pharmaceutical preparations by high performance liquid chromatography

Anodic Voltammetry of Ciprofloxacin and its Analytical Applications

Simultaneous Separation and Determination of Quinolones in Pharmaceuticals by Micellar Liquid Chromatography

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