High-performance sono/nano-catalytic system: Fe3O4@Pd/CaCO3-DTT core/shell nanostructures, a suitable alternative for traditional reducing agents for antibodies

Antimicrobial therapeutic enhancement of levofloxacin via conjugation to a cell‐penetrating peptide: An efficient sonochemical catalytic process

“…The reverse‐phase high‐performance liquid chromatography (RP‐HPLC) and liquid chromatography–mass (LC‐mass) chromatograms of the applied CPP chain are illustrated in Figures S1 and S2. All of the essential structural analyses on the applied heterogeneous magnetic sono/nano catalytic systems have been performed and interpreted in our previous reports 19,26 . Fourier‐transform infrared (FT‐IR) and nuclear magnetic resonance (NMR) spectra of the synthesized Gly‐Ala dipeptide were obtained through (Shimadzu) FT‐IR‐8400s and Varian Unity Inova 500 MHz, respectively.…”

“…Recently, we have found out that the function of these heterogeneous catalytic systems could be greatly enhanced by applying the ultrasound waves. In our previous reports, we comprehensively discussed the substantial synergistic catalytic effect between the magnetic nanoparticles (MNPs) and the ultrasound waves with a determined frequency and power density 18–20 . Concisely, ultrasonication leads to obtain high reaction yield during a short reaction time, under a milder condition.…”

“…In this study, we intend to introduce a convenient synthetic strategy for a novel medicinal conjugation including CPP hexapeptide and LVX, which passes through a comparative viewpoint between two different heterogeneous magnetic catalytic systems. One of these nanocatalysts includes iron oxide MNPs functionalized with dithiothreitol (Fe 3 O 4 @Pd/CaCO 3 ‐DTT) 19 (from here onwards is called as catalyst A), and another one includes silver and iron oxide MNPs functionalized with isothiazolone ring (Ag‐Fe 3 O 4 @IT) 26 (from here onwards is called as catalyst B). In our previous reports, we have used these catalytic systems for different aims including peptide bond formation and reduction of the antibodies.…”

“…From the structural aspect, presence of the sulfur atom on the NPs surfaces is common between these two catalytic systems and is considered as the main catalytic active site. The preparation methods of these heterogeneous catalytic systems (A and B) have been submitted in details, in our previous reports 19,26 …”

Method screening for conjugation of the small molecules onto the vinyl-coated Fe3O4/silica nanoparticles: highlighting the efficiency of ultrasonication

“…Sonochemistry investigates the effect of high-frequency sound waves on the chemical and physical properties of materials. How it could be a great driving force for chemical reactions like forming or breaking covalent bonds also belongs to this field of study [1][2][3][4][5]. Several methods are used for the surface modification of iron oxide nanoparticles (Fe 3 O 4 NPs) including reflux, ball milling, microwave radiation, autoclave at high temperatures and pressures, and ultrasonication [6][7][8].…”