High pressure jet spray drying of condensed skim milk results in powders with enhanced interfacial properties

Voronin, Grace Lewis; Hettiarachchi, Charith A.; Harte, Federico

doi:10.1016/j.jfoodeng.2020.110249

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…To limit this aggregation, biopolymers with opposite charges such as proteins and carbohydrates have been utilized as protectants through spray drying to improve the kinetics and mechanical stability of liposomes [ 51 , 52 ]. Spray drying parameters including temperature, biopolymer type, biopolymer amount and spray gas flow affect the characteristics and morphology of the final powder [ 53 , 54 , 55 ]. The temperature of spray drying is related to the evaporation rate of moisture, the higher temperature and the faster evaporation rate.…”

Section: Post-processing Techniques For Liposomesmentioning

confidence: 99%

Post-Processing Techniques for the Improvement of Liposome Stability

Chuesiang

Shin

et al. 2021

Pharmaceutics

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Liposomes have been utilized as a drug delivery system to increase the bioavailability of drugs and to control the rate of drug release at the target site of action. However, the occurrence of self-aggregation, coalescence, flocculation and the precipitation of aqueous liposomes during formulation or storage can cause degradation of the vesicle structure, leading to the decomposition of liposomes. To increase the stability of liposomes, post-processing techniques have been applied as an additional process to liposomes after formulation to remove water and generate dry liposome particles with a higher stability and greater accessibility for drug administration in comparison with aqueous liposomes. This review covers the effect of these techniques including freeze drying, spray drying and spray freeze drying on the stability, physicochemical properties and drug encapsulation efficiency of dry liposomes. The parameters affecting the properties of liposomes during the drying process are also highlighted in this review. In addition, the impact of using a protective agent to overcome such limitations of each process is thoroughly discussed through various studies.

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Section: Post-processing Techniques For Liposomesmentioning

confidence: 99%

Post-Processing Techniques for the Improvement of Liposome Stability

Chuesiang

Shin

et al. 2021

Pharmaceutics

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“…However, the action mechanisms are totally different. The bulk materials are first transferred into solution, and later the mechanical forces are applied on the solutions, by which the liquid state is easy to be downsized [10,11].…”

Section: Nanofabrication and Key Points For Fabricating Janus Nanofibersmentioning

confidence: 99%

Nanofabrication of Janus Fibers through Side-by-Side Electrospinning - A Mini Review

Lv¹,

Yu²,

Wang³

et al. 2021

MAHIG

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Janus and core-shell nanostructures are the most fundamental structural characteristics for comprising all types of multiplechamber structures. The facile preparation of Janus structure is one of the most difficult challenges in the field of nanofabrication, whose production can pave a broad way for generating a wide variety of hierarchic nanostructures. Based on several most recent reports, this mini review provides some comments on the generation of Janus nanofibers on the following topics: (1) the key points for fabricating Janus nanofibers using side-by-side electrospinning; (2) the strategies for functionalizing the Janus nanofibers; and (3) the possibilities of complex nanostructures started from the two-chamber Janus structures.

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