2013
DOI: 10.1016/j.vetmic.2013.03.017
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High prevalence of rat hepatitis E virus in wild rats in China

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Cited by 61 publications
(63 citation statements)
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“…Following that report, we and other groups have also found HEV-C1 in Vietnam, U.S.A., Indonesia, Denmark and China [10, 12, 13, 14, 17], suggesting a worldwide distribution of HEV-C1. HEV-C1 is genetically distant from human HEV: nucleotide sequence identity of entire genome is about 55%, and amino acid sequence identities of ORF1, ORF2 and ORF3 proteins are about 50%, 55% and 30%, respectively [4, 7].…”
supporting
confidence: 78%
“…Following that report, we and other groups have also found HEV-C1 in Vietnam, U.S.A., Indonesia, Denmark and China [10, 12, 13, 14, 17], suggesting a worldwide distribution of HEV-C1. HEV-C1 is genetically distant from human HEV: nucleotide sequence identity of entire genome is about 55%, and amino acid sequence identities of ORF1, ORF2 and ORF3 proteins are about 50%, 55% and 30%, respectively [4, 7].…”
supporting
confidence: 78%
“…The relationship between different genders of pets was weak enough that it might not represent a risk factor for HEV infection. Rodents are one probable reservoir, especially for companion animals, and it has recently been reported in Japan and China that wild rats have been found to be infected with HEV [24], [25]. A recent study suggested that rodent hunting by cats could be a reason for the higher levels of HEV antibodies [8].…”
Section: Discussionmentioning
confidence: 99%
“…Genotype C1 includes strains isolated from rat (Figure 1). However, some variants with incomplete sequences, isolated from bandicoot and Asian musk shrew, cluster also in this genotype [58,59]. The phylogeny analysis of the full genomes available shows three different clusters within this genotype that may constitute three possible subtypes (Figure 1).…”
Section: Hev Phylogenymentioning
confidence: 99%