High Prevalence of Sinusitis in Children with Henoch-Schönlein Purpura

Nakaseko, Haruna; Uemura, Osamu; Nagai, Takuhito; Yamakawa, Satoshi; Hibi, Yoshiko; Yamasaki, Yasuhito; Yamamoto, Masaki

doi:10.1155/2011/562638

Cited by 15 publications

(13 citation statements)

References 8 publications

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“…Previous upper respiratory infections were reported in patients with HSP. 14 15 Exposure to viral infections among clustered children in daycare centers, or preschools might contribute to the fact that HSP is common in young children and rare during summer.…”

Section: Discussionmentioning

confidence: 99%

Ten-year Nationwide Population-based Survey on the Characteristics of Children with Henoch-Schӧnlein Purpura in Korea

et al. 2018

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BackgroundHenoch-Schӧnlein purpura (HSP) is a common vasculitis of childhood. Though HSP is usually self-limiting, severe complications can occur. The management for this condition has not been established yet. Thus, this nationwide study aimed at investigating epidemiological characteristics of children with HSP in Korea. The patterns of clinical practice with regard to the complications of the condition were also investigated.MethodsThis is a national population-based study that used the National Health Insurance Database. Children below 18 years who were diagnosed with HSP in Korea between 2006 and 2015 were enrolled. Data, such as age, sex, yearly and monthly distribution of HSP, hospitalization, re-hospitalization, comorbidities, and interventions were obtained. The use of steroids was also analyzed.ResultsA total of 56,841 children were enrolled. The annual incidence of HSP was 55.9 per 100,000 children. The peak age was 5 years. Spring was the most prevalent season. Sex (male) and young age (< 9 years) were risk factors of hospitalization. Younger children were more likely to be re-hospitalized and suspected with intussusception, arthritis, and nephritis. Only 4 children received laparotomy. In total, 57% were managed with steroids, and mean durations of medication were 4–5 days. Children who were hospitalized and those with comorbidities used steroids more frequently (P < 0.001).ConclusionThe annual incidence of HSP is 55.9 per 100,000 children which is higher in Korea than that in other countries. Younger children can have a more severe clinical course. This nationwide survey provides valuable information to understand HSP in children and to inspire further research on HSP.

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Section: Discussionmentioning

confidence: 99%

Ten-year Nationwide Population-based Survey on the Characteristics of Children with Henoch-Schӧnlein Purpura in Korea

et al. 2018

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“…Among the etiological factors rarely mentioned is Moraxella catarhalis. Most cases are caused by bacteria Streptococcus pyogenes, Haemophilus influenzae, or Staphylococcus aureus [17] and viruses (e.g., adenoviruses, Epstein-Barr virus, or parvovirus) [18] . The drugs of choice are still glucocorticoids which reduce the risks of developing complications.…”

Section: Discussionmentioning

confidence: 99%

Henoch-Schönlein purpura

Zdanowska¹,

Owczarczyk‐Saczonek²,

Placek³

2016

J Surg Dermatol

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Henoch-Schönlein purpura (HSP) is an acute, systemic vasculitis which usually occurs in young adults and children. The skin involvement may lead to the manifestation of symptoms associated with vasculitis in intestines, kidneys, and the central nervous system. The incidence of bowel perforation in course of HSP is very seldom and it occurs about 10 days after the appearance of the first symptoms. We present a 23-year-old male patient with jejunal intussusception in the course of HSP. The patient was operated urgently with resection of part of the small intestine. Adults rarely suffer from the occurrence of abdominal pain and fever, but sometimes they require careful monitoring and surgical intervention because misdiagnosis can be life threatening.

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“…Children have commonly unilateral involvement in AFS compared to adults [68]. Sinusitis forms the initiating focus in 50% of the Henoch-Schonlein purpura (HSP) in children [69]. …”

Section: Clinical Featuresmentioning

confidence: 99%

Rhinosinusitis in Children

Shahid

2012

ISRN Otolaryngology

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Rhinosinusitis is the inflammation of the mucous membranes of nose and paranasal sinus(es). 5–13% of upper respiratory tract infections in children complicate into acute rhinosinusitis. Though not life threatening, it profoundly affects child's school performance and sleep pattern. If untreated, it could progress to chronic rhinosinusitis (CRS). The pathogens involved in perpetuation of CRS consist of multidrug-resistant mixed microflora. CRS is challenging to manage and could further extend to cause eye or intracranial complications. In children, CRS diagnosis is often either missed or incomprehensive. Due to this, morbidity and strain on healthcare budget are tremendous. Flexible fiberoptic endoscopy has revolutionized management of CRS. Its utility in children is being increasingly recognized. Optimal management entails specific appropriate antimicrobials as well as treatment of underlying causes. The aim is to normalize sinus anatomy and physiology and regain normal mucociliary function and clearance.

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High Prevalence of Sinusitis in Children with Henoch-Schönlein Purpura

Cited by 15 publications

References 8 publications

Ten-year Nationwide Population-based Survey on the Characteristics of Children with Henoch-Schӧnlein Purpura in Korea

Ten-year Nationwide Population-based Survey on the Characteristics of Children with Henoch-Schӧnlein Purpura in Korea

Henoch-Schönlein purpura

Rhinosinusitis in Children

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